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- Grade Range
- 9th - 12th
- Rating

Students use Biology Workbench to explore DNA sequence data for the GULOP gene in humans, chimpanzees, orangutans, and crab-eating macaques and the beta globin gene and its pseduogene in humans, gorillas, and chimpanzees. Full Review »
- Grade Range
- 10th - 12th
- Rating

Students study the details of DNA restriction analysis and how RFLP's are used to locate genes on a map of DNA. Full Review »
- Grade Range
- 9th - 12th
- Rating

Students compare/constrast DNA sequence data for a portion of the rat GULO gene to the corresponding sequence in the inactive GULO gene in humans, chimpanzees, orangutans, and crab-eating macaques by identifying the shared sequences in their alignment. Full Review »
- Grade Range
- 9th - 12th
- Rating

Students explore how gene sequence analysis can be used to examine phylogenetic similarities of different organisms. Students work in groups to simulate a gel electrophoresis separation of fragments using poster board to create their gel. Full Review »
- Grade Range
- 9th - 11th
- Rating

Students describe how inserting, deleting, or subsituting DNA segments can alter a gene. They explore mutations in the gene sequence and the types of disorders that may result. Full Review »
- Grade Range
- 9th - 12th
- Rating

Students explore the Human Genome Project (HGP). Students research a fact situation, examine genetic data given, and discuss choices available for a solution. Students consider the ethical question and consequences of each choice. Full Review »
- Grade Range
- 9th
- Rating

Students use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the CF gene. Students make comparisons between base sequences of pairs of chromosomes from individuals who are not affected by CF and those who are. Full Review »
- Grade Range
- 9th - 12th
- Rating

Students simulate the Sanger method of DNA sequencing using color pop-beads as a representation of nucleotides and dideoxynucleotides. Students assemble DNA sequences and run their sequences through a "sequencing gel" and sketch what the DNA sequence bands should look like. Full Review »
- Grade Range
- 9th
- Rating

Students determine nucleotide sequences. They identify those base sequences that are normal, those that are normal variants and those that cause cystic fibrosis. Students use DNA nucleotide sequences to determine amino acid sequences. Full Review »
- Grade Range
- 9th - 12th
- Rating

Students are introdued to laboratory techniques that distinguish differences between species using current genomic practices. They comprehend DNA structure and function. Students define the terms gene theory and sequencing. Full Review »

