{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='A study of more than 600 older veterans with mild to moderate Alzheimer\u0026#39;s disease showed that high doses of vitamin E delayed the decline in daily living skills, such as getting oneself dressed, by about six months over a two-year period. (Dec. 31)' data-url='/boclips/videos/5c54bb26d8eafeecae122e2e' data-video-url='/boclips/videos/5c54bb26d8eafeecae122e2e' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nA study of more than 600 older veterans with mild to moderate Alzheimer\u0026#39;s disease showed that high doses of vitamin E delayed the decline in daily living skills, such as getting oneself dressed, by about six months over a two-year period. (Dec. 31)\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eFOR CLEAN VERSION SEE STORY NUMBER: apus003172Vitamin E might slow the progression of mild to moderate Alzheimer's disease, researchers are reporting. It's the first time any treatment has been shown to alter the course of dementia at...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eFOR CLEAN VERSION SEE STORY NUMBER: apus003172\u003cbr/\u003eVitamin E might slow the progression of mild to moderate Alzheimer's disease, researchers are reporting. It's the first time any treatment has been shown to alter the course of dementia at that stage.\u003cbr/\u003eIn a study of more than 600 older veterans, high doses of the vitamin delayed the decline in daily living skills, such as making meals, getting dressed and holding a conversation, by about six months over a two-year period.\u003cbr/\u003eThe benefit was equivalent to keeping one major skill that otherwise would have been lost, such as being able to bathe without help. For some people, that could mean living independently rather than needing a nursing home.\u003cbr/\u003eVitamin E did not preserve thinking abilities, though, and it did no good for patients who took it with another Alzheimer's medication. But those taking vitamin E alone required less help from caregivers _ about two fewer hours each day than some others in the study.\u003cbr/\u003eThe U.S. Department of Veterans Affairs sponsored the study, published Tuesday by the Journal of the American Medical Association.\u003cbr/\u003eNo one should rush out and buy vitamin E, several doctors warned. It failed to prevent healthy people from developing dementia or to help those with mild impairment (\"pre-Alzheimer's\") in other studies, and one suggested it might even be harmful.\u003cbr/\u003eStill, many experts cheered the new results after so many recent flops of once-promising drugs.\u003cbr/\u003eAbout 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. There is no cure and current medicines just temporarily ease symptoms.\u003cbr/\u003eResearchers don't know how vitamin E might help, but it is an antioxidant, like those found in red wine, grapes and some teas. Antioxidants help protect cells from damage that can contribute to other diseases, says the federal Office on Dietary Supplements. Many foods contain vitamin E, such as nuts, seeds, grains, leafy greens and vegetable oils. There are many forms, and the study tested a synthetic version of one _ alpha-tocopherol _ at a pharmaceutical grade and strength, 2,000 international units a day.\u003cbr/\u003eYears ago, another study found that the same form and dose helped people with more advanced Alzheimer's, and many were prescribed it. But vitamin E fell out of favor after a 2005 analysis of many studies found that those taking more than 400 units a day were more likely to die of any cause.\u003cbr/\u003eThe new study involved 613 veterans, nearly all male, 79 years old on average, with mild to moderate Alzheimer's, at 14 VA centers. All were already taking Aricept, Razadyne or Exelon _ widely used, similar dementia medicines.\u003cbr/\u003eParticipants were placed in four groups and given either vitamin E, another dementia medicine called memantine (brand name Namenda), both pills or dummy pills. No one knew which treatment anyone was getting until the study ended.\u003cbr/\u003eAfter a little more than two years of follow-up, those on vitamin E alone had a 19 percent lower annual rate of decline in daily living skills compared to the placebo group. Memantine made no difference, and vitamin E did not affect several tests of thinking skills.\u003cbr/\u003eHeather Snyder, director of medical and scientific operations for the Alzheimer's Association, said the group's position is that \"no one should take vitamin E for Alzheimer's disease or other memory issues except under the supervision of a physician,\" because it can interfere with blood thinners, cholesterol drugs and other medicines.\u003cbr/\u003eThe new results also need to be verified in a fresh study that includes more women and minorities, she said.\u003cbr/\u003e1. SOUNDBITE: Martha Clare Morris, Professor Epidemiology, Rush University: \u003cbr/\u003e\"This was a randomized trial to examine the effects of 2000 international units of vitamin E per day or memontine 20 mgs a day or the combination therapy in comparison to a placebo.// The trial found that vitamin E alone significantly slowed the progression by about 6.2 months over the course of the trial.//the effect was equivalent to say being able to bathe being able to dress oneself so very basic functions that would require care givers to assist a person in doing these activities.//vitamin E has very few adverse effects compared to medications and is a cheap medication as well. So the fact that it could maybe delay somebody from going into the nursing home or reduce the amount of caregiver effort is a significant contribution to the field.//there's very little to indicate with this study that they're actually reducing or stalling the progression of the disease.//this effect seems to be very specific to people with mild to severe AD and if people want to take vitamin E that don't have Alzheimer's disease there isn't evidence to show that vitamin E at this dose level would prevent one from getting Alzheimer's disease.\"\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\n\u003cspan id='read_more'\u003eRead More\u003c/span\u003e\n\u003c/button\u003e\n\u003cdiv 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(Dec. 31)\" href=\"/subscription/new\"\u003e\u003cimg class=\"resource-img img-thumbnail img-responsive z-10 lp-boclips-thumbnail w-full h-full lozad\" alt=\"A study of more than 600 older veterans with mild to moderate Alzheimer\u0026#39;s disease showed that high doses of vitamin E delayed the decline in daily living skills, such as getting oneself dressed, by about six months over a two-year period. (Dec. 31)\" title=\"A study of more than 600 older veterans with mild to moderate Alzheimer\u0026#39;s disease showed that high doses of vitamin E delayed the decline in daily living skills, such as getting oneself dressed, by about six months over a two-year period. 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