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\nOne Carbon Metabolism | Tetrahydrofolate and the Folate Cycle\n

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\n\nPublisher:\n\nJJ Medicine\n\n\n
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\nLesson on One Carbon Metabolism, the role of tetrahydrofolate and the folate cycle. Tetrahydrofolate (THF) is derivative of folic acid (Vitamin B9), which is acquired from dietary sources. Tetrahydrofolate (THF) in various forms...\nLesson on One Carbon Metabolism, the role of tetrahydrofolate and the folate cycle. Tetrahydrofolate (THF) is derivative of folic acid (Vitamin B9), which is acquired from dietary sources. Tetrahydrofolate (THF) in various forms (N5,N10-methylene THF etc.) acts as a carbon donor, allowing cells to produce nucleic acids, amino acids and methionine and s-adenosyl methionine in the activated methyl cycle.
Hey guys! In this lesson you will learn about one carbon metabolism, tetrahydrofolate and its role in producing various cellular products needed for purine and pyrimidine synthesis. You will also learn which dietary sources contain folic acid (folate), how folate is processed to tetrahydrofolate, and you will also learn the enzymes of the pathway. The anti-cancer medications known as methotrexate and 5-fluorouracil and their enzyme targets will also be discussed. Finally, you will also learn how the one carbon metabolism pathway is connected with the activated methyl cycle and methionine metabolism.

Hope you all find it helpful.
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Resource Details

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Media Length
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12:42
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Grade
Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nJJ Medicine\n\n
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Date
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2018
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Language
English
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Audiences
For Teacher Use
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Usage Permissions
Fine Print: Educational Use
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one carbon metabolism, one carbon cycle, one carbon transfer, one carbon metabolism pathway, one carbon metabolism folate, folate cycle, folate cycle diagram, folate cycle explained, folate cycle usmle, folate methionine cycle, tetrahydrofolate cycle, tetrahydrofolate synthesis, tetrahydrofolate metabolism, tetrahydrofolate function, tetrahydrofolate vitamin, tetrahydrofolate mechanism, folate metabolism, folate metabolism pathway, one carbon metabolism biochemistry, dietary sources, fortified foods, electron donor, thymidylate synthase, dna synthesis, catecholamine biosynthesis, purine synthesis, methionine synthase, main purpose, folic acid, recycled back, critically important, cell requires, methionine, back, purpose, requires, important, form, produce, nadph, acts, dihydrofolate, homocysteine, cell, tetrahydrofolate, folate, process, enzyme
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