{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='What Is Metabolic Syndrome? How To Check For It.' data-url='/boclips/videos/65112e8060795c4682b86576' data-video-url='/boclips/videos/65112e8060795c4682b86576' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nWhat Is Metabolic Syndrome? How To Check For It.\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eHave you ever heard of metabolic syndrome? It’s something you should know about if you take antipsychotic medications. All of the antipsychotic medications increase the risk of developing metabolic syndrome. Some do it more than others. ...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eHave you ever heard of metabolic syndrome? It’s something you should know about if you take antipsychotic medications. All of the antipsychotic medications increase the risk of developing metabolic syndrome. Some do it more than others. \u003cbr/\u003e \u003cbr/\u003e Metabolic syndrome is not a disease, but it’s a set of risk factors that increase your risk of heart disease, diabetes and stroke.\u003cbr/\u003e \u003cbr/\u003e Here are the five risk factors that constitute metabolic syndrome.\u003cbr/\u003e 1. Increase waist circumference Men greater than 40 inches\u003cbr/\u003e Women greater than 35 inches\u003cbr/\u003e You get this number by using a tape measure. You start at your hip bone and wrap it around your waist at the level of your navel.\u003cbr/\u003e \u003cbr/\u003e 2. Increased blood pressure of greater than 135/85\u003cbr/\u003e 3. Triglyceride level greater than 150 mg/dL\u003cbr/\u003e 4. HDL cholesterol less than 40 mg/dL in men \u003cbr/\u003e less than 50 mg/dL in women\u003cbr/\u003e \u003cbr/\u003e HDL is considered good because it absorbs excess cholesterol and carries it back to the liver for processing. So high levels of HDL actually lower your risk of heart attack and stroke. This is why having a high total cholesterol isn’t necessarily bad. It depends on how high it is. But if you have a high HDL, it’s going to raise your total cholesterol. LDL cholesterol is considered bad because when you have too much of it, it can deposit itself on your artery walls and create plaques that narrow your arteries. This contributes to heart disease and risk of stroke. So you want to keep you LDL as low as possible. \u003cbr/\u003e \u003cbr/\u003e 5. Fasting blood glucose equal or greater than 100mg/dL \u003cbr/\u003e This is a measure of how much glucose or sugar you have in your blood when you haven’t eaten anything for at least 8 hours. Insulin is the hormone produced by the pancreas that processes the glucose from the food you eat. \u003cbr/\u003e \u003cbr/\u003e Glucose levels\u003cbr/\u003e Normal = Blood glucose under 100mg. \u003cbr/\u003e Prediabetes = Blood glucose of 100-125 \u003cbr/\u003e Diabetes = Blood glucose greater than 126mg/dl\u003cbr/\u003e \u003cbr/\u003e According the American Heart Association, you need 3 out of five of these to be diagnosed with metabolic syndrome.\u003cbr/\u003e \u003cbr/\u003e What makes this happen?\u003cbr/\u003e There are medical conditions that can cause metabolic syndrome, and obesity is a common one. \u003cbr/\u003e \u003cbr/\u003e What does it mean to be obese?\u003cbr/\u003e Obesity is defined by your body mass index (BMI). \u003cbr/\u003e BMI = weight in kilograms/height in meters2\u003cbr/\u003e \u003cbr/\u003e There are handy calculators online that make it easy for you to input your height in feet and inches and your weight in pounds without having to convert to metric units. \u003cbr/\u003e BMI Ranges\u003cbr/\u003e Normal – 18.5 – 24. 9\u003cbr/\u003e Overweight - 25 – 29.9\u003cbr/\u003e Obese - 30 or greater\u003cbr/\u003e \u003cbr/\u003e There are many things that can lead to obesity. But in psychiatry, the antipsychotic medications we use can cause a lot of weight gain and lead to metabolic syndrome. \u003cbr/\u003e \u003cbr/\u003e A 2017 article ranked the antipsychotic medications in order of weight gaining tendency. \u003cbr/\u003e The three causing the greatest weight gain were: \u003cbr/\u003e Clozapine\u003cbr/\u003e Olanzapine\u003cbr/\u003e Chlorpromazine\u003cbr/\u003e \u003cbr/\u003e References\u003cbr/\u003e Douma LG, Gumz ML. Circadian clock-mediated regulation of blood pressure. Free Radic Biol Med. 2018;119:108-114. doi:10.1016/j.freeradbiomed.2017.11.024\u003cbr/\u003e \u003cbr/\u003e Dayabandara M, Hanwella R, Ratnatunga S, Seneviratne S, Suraweera C, de Silva VA. Antipsychotic-associated weight gain: management strategies and impact on treatment adherence. Neuropsychiatr Dis Treat. 2017;13:2231-2241. Published 2017 Aug 22. doi:10.2147/NDT.S113099\u003cbr/\u003e \u003cbr/\u003e Mitchell AJ, Vancampfort D, De Herdt A, Yu W, De Hert M. Is the prevalence of metabolic syndrome and metabolic abnormalities increased in early schizophrenia? A comparative meta-analysis of first episode, untreated and treated patients. Schizophr Bull. 2013 Mar; 39(2):295-305.\u003cbr/\u003e \u003cbr/\u003e Bazo-Alvarez JC, Morris TP, Carpenter JR, Hayes JF, Petersen I. Effects of long-term antipsychotics treatment on body weight: a population-based cohort study [published online November 14, 2019]. J Psychopharmacol. doi:10.1177/0269881119885918\u003cbr/\u003e \u003cbr/\u003e Feingold KR, Grunfeld C. Introduction to Lipids and Lipoproteins. [Updated 2018 Feb 2]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available \u003ca href='https://www.ncbi.nlm.nih.gov/books/NB...' target='_blank' rel='nofollow'\u003efrom\u003c/a\u003e\u003cbr/\u003e \u003cbr/\u003e Grajales D, Ferreira V, Valverde ÁM. Second-Generation Antipsychotics and Dysregulation of Glucose Metabolism: Beyond Weight Gain. Cells. 2019;8(11):1336. Published 2019 Oct 29. doi:10.3390/cells8111336\u003cbr/\u003e \u003cbr/\u003e \u003cbr/\u003e \u003cbr/\u003e Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. 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