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\nMaxam Gilbert Sequencing\n

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\nMaxam–Gilbert sequencing is a method of DNA sequencing developed by Allan Maxam and Walter Gilbert in 1976–1977. This method is based on nucleobase-specific partial chemical modification of DNA and subsequent cleavage of the DNA backbone...\nMaxam–Gilbert sequencing is a method of DNA sequencing developed by Allan Maxam and Walter Gilbert in 1976–1977. This method is based on nucleobase-specific partial chemical modification of DNA and subsequent cleavage of the DNA backbone at sites adjacent to the modified nucleotides Maxam–Gilbert sequencing was the first widely adopted method for DNA sequencing, and, along with the Sanger dideoxy method, represents the first generation of DNA sequencing methods. Maxam–Gilbert sequencing is no longer in widespread use, having been supplanted by next-generation sequencing methods.\n
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Resource Details

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Curator Rating
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Educator Rating
Not yet Rated
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Media Length
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10:34
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Grade
9th - Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nBioMagica\n\n
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Date
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2019
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Language
English
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Audiences
For Teacher Use
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Usage Permissions
Fine Print: Educational Use
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Concepts

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gel electrophoresis, electrophoresis, bands, thymine, cytosine, adenine
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Additional Tags

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csir, net, reaction tubes, banding pattern, dilute hcl, chemical treatment, prime end, end labeling, single strand, smaller fragments, made randomly, fourth position, sequencing method, strand, made, sequence, fragments, method, breaks, number, cuts, mixture, position, step, label, agaro
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Classroom Considerations

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Video is ad-free
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\n\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: Maxam Gilbert Sequencing\" href=\"/subscription/new\">\"Maxam\n\n
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