Towson University
Looking Into Lactase: Guided Inquiry
Milk does a body good ... unless, of course, someone is lactose intolerant. Pupils play the role of pharmaceutical scientists in a guided inquiry lab about lactase. Lab groups collaborate to learn more about lactose intolerance, how...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Howard Hughes Medical Institute
Lactase Persistence: Evidence for Selection
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Howard Hughes Medical Institute
Patterns in the Distribution of Lactase Persistence
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Howard Hughes Medical Institute
Got Lactase? Blood Glucose Data Analysis
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...
Towson University
Looking Into Lactase: Structured Inquiry
Why is lactase important? Biology scholars explore enzyme function in a structured inquiry lab. The activity tasks lab groups with observing how temperature and pH affect enzyme activity, as well as determining which milk products...
Howard Hughes Medical Institute
Regulation of the Lactase Gene
All human infants are lactose tolerant, yet some adults are lactose intolerant—why is that? Individuals discover the process of gene mutation through a study of the lactase gene (LCT). They understand the geographic connections,...
Curated OER
Enzymes Help Us Digest Food ~ Introduction to Sugars and Enzymes
After an explanatory introduction to sugars and enzyme activity, biochemists discover whether lactase is needed to digest lactose, sucrose, and milk as a whole. High school science lab skills are required for these investigations.
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Curated OER
Lactose & Lactase
Students examine the characteristics of lactose and lactase. In this enzyme lesson plan students study the lactose in milk and its rate of dissolution.
Curated OER
Milk Makes Me Sick
High schoolers experiment with lactase to find out how milk sugar is broken down in the body. In this enzyme lesson, students use glucose strips to investigate the breakdown of lactose into glucose and galactose for milk digestion in the...
Curated OER
Enzyme Action
Students work with models of substrates and of enzymes and test the digestion of lactose with lactase. They determine if digestion of lactose has or has not occurred.
Curated OER
Are Enzymes Specific for Their Substrates?
Young scholars discover enzyme to substrate specificity. The experiment uses samples of glucose and lactose in combination with the enzyme lactase. Students observe the reaction between the lactose and the lactase; the lack of a...
Howard Hughes Medical Institute
Milk—How Sweet Is It?
Have you ever wondered why some people are lactose intolerant? Participants test simulated patients in a hands-on lab activity to find out! They learn about lactose intolerance by performing an experiment, analyzing data, and drawing...
Howard Hughes Medical Institute
Pedigrees and the Inheritance of Lactose Intolerance
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
Curated OER
Enzyme Practice Sheet Key
In this enzyme worksheet, students solve 6 problems including questions about how enzymes work, graphs of the relationship between enzyme and substrate and structures of enzymes.
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