Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Towson University
Mystery of the Crooked Cell
Can your class solve the Mystery of the Crooked Cell? Junior geneticists collaborate to learn about sickle cell anemia in a fascinating lesson plan. The included materials help them to examine the genetic factors behind the disease...
Howard Hughes Medical Institute
Patterns in the Distribution of Lactase Persistence
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Teach Engineering
See the Genes
"If you can't explain it simply, you don't understand it well enough" - Albert Einstein. The sixth installment of a seven-part series teaches young scientists about the importance of being able to communicate scientific research and...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Teach Engineering
Show Me the Genes
Give your class a chance to show what they know. In the last installment of a seven-part series, pupils summarize and review what they have learned in the series. They present their solutions for creating a biosensor to detect cancer...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Curated OER
The Case of Regulation in Cells
After your biologists have learned about transcription, translation, and gene regulation, they work in a small group to create a poster of a system that serves as an analogy of the gene regulation process. They share their creations with...
Curated OER
Gene Puzzles
Students come to understand that in sexually reproducing organisms, such as humans, typically half of the genes come from each parent.
Students examine a fictional pedigree and determine which gene is responsible for a given trait. The...
Curated OER
Genes at Work
Students explore and discuss genetics stories and answer questions about genetic outcomes of offspring. In this genetics instructional activity, students read genetics stories on a web site. Students use a chart to answer questions...
Howard Hughes Medical Institute
Winogradsky Columns: Microbial Ecology in the Classroom
Winogradsky columns are ideal for observing the role of bacteria and other microorganisms in an ecosystem. This student activity guide is complete with data tables for observations and analysis questions for processing what was observed....
Curated OER
Understanding: The Power of Genes
Students study genes and the new information on genetics. In this genes lesson plan students write essays on their information on genetics.
Curated OER
RNA and Gene Expression
In this RNA and gene expression activity, students match the letter of the description that best matches the term as it relates to gene expression. Students also answer questions as it relates to the process of transcription and...
Teach Engineering
Tell Me Doc—Will I Get Cancer?
Can you beat the odds of cancer? In the first installment of a seven-part series, future biomedical engineers consider how to detect and diagnose cancer. An article on biosensors provides useful information toward this goal.
Curated OER
How Big is a Gene?
Students model the size and structure of a bacterial chromosome. In this genetics instructional activity, students attempt to fit strands of thread into a gelatin capsule. They relate the activity to the coiling of DNA into chromosomes...
Curated OER
Genes and Gene Technology
In this genetics worksheet, students complete 3 short answer, a word puzzle, and 7 word games about genetic traits.
Curated OER
Reaching Into Your Genes
Students interact with a video to explore the basis for the science of chromosomes. They perform a chromosomal analysis called a karyotype and explore how seemingly minute errors in chromosomes can lead to devastating illnesses.
Howard Hughes Medical Institute
How Novel Icefish Genes Can Improve Human Health
Designed to accompany the 13-minute video The Making of the Fittest: The Birth and Death of Genes, this handout serves as both a viewing guide during the video and an analysis of how the adaptations of the icefish might help treat some...
Curated OER
Producing a Strain of E. coli that Glows in the Dark
Students observe the experimental process called bacterial transformation and demonstrate phenotype changes in bacteria that have been transformed with an antibiotic-resistance gene and a metabolic marker. They create a luminescent...
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Howard Hughes Medical Institute
Survival of the Fittest - Variations in the Clam Species Clamys sweetus
It's not often that you come across a clever laboratory activity that is both imaginative and comprehensive! Using M&M's and Reese's peanut butter candies to represent two different clam species, young biologists test for "relative...
Curated OER
Gene Control in Eukaryotes
In this gene control in eukaryotes worksheet, students complete a table with information about the process of translation and transcription. Students also explain the process of post-transcription and the modifications involved.
Curated OER
Design Yer Genes
Seventh graders explore general structure of and natural changes that occur in DNA strands, and discuss concept of genetic engineering by creating small portion of strawberry chromosome with three genes, modeling naturally occurring...