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Interactive
Concord Consortium

3D Exploration of Bound Antibody and Antigen

For Students 9th - 12th Standards
Our body manufactures antibodies that are the exact shape for the antigens it encounters. The simulation shows a 3-D model of an antibody and antigen pairing. It allows young scientists to explore the complementary shapes.
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Activity
Exploratorium

Antibody Attack - Discover How Antibodies Launch Attacks on Invaders

For Teachers 6th - 12th
Jump into the action and help antibodies defend against an antigen attack! Investigators match antibodies with antigens to model the body's identification and recall of specific pathogens. Young biologists also recognize that each...
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Worksheet
Curated OER

Were the babies switched? – The Genetics of Blood Types

For Students 9th - 12th
Human biology or genetics learners apply their knowledge to a unique situation: two newborn baby girls being possibly switched in the hospital. The engaging activity ends with a Punnett squares assignment in which pupils evaluate whether...
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Worksheet
Curated OER

Antibody Center Template

For Students 8th - 12th
In this antibodies learning exercise, students use model diagrams of antigens, antibodies and blood cells to develop a visual understanding of the immune system. They draw diagrams of antibodies and antigens attached to each other and...
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Lesson Plan
Curated OER

Antibodies and Antigens: Fitting Together

For Teachers 8th - 10th
Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require pupils to explain in writing how each antibody works...
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Lesson Plan
Curated OER

Antibodies

For Teachers 9th - 12th
Students conduct a series of exploration activity on how vaccines and antibodies work. In this biology lesson, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting immune responses.
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Lesson Plan
Curated OER

Antigens versus Antibodies "KO'd in Round Three" The Third Line of Defense of the Human Immune System

For Teachers 7th
Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.
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Lesson Plan
Curated OER

Antigens

For Teachers 8th - 12th
Learners examine antigens including ones found in humans.  For this immune lesson students complete several experiments in relation to antigens and antibodies.
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Lesson Plan
Curated OER

Disease Diagnosis

For Teachers 9th - 12th
Students comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...
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Worksheet
Curated OER

The Immune System

For Students 11th - Higher Ed
Activate the immune system in the brains of your biologists! This worksheet calls upon learners to explain the structure, function, and problems associated with the immune system. This worksheet is helpful for the advanced placement...
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Lesson Plan
Curated OER

Teaching Multiple Alleles

For Teachers 9th - 12th
Students view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...
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Lesson Plan
Curated OER

Operation Anitbody

For Teachers 9th - 12th
Students identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case studies,...
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Worksheet
Curated OER

Your Immune System

For Students 7th - 9th
In this immune system worksheet, students describe an antibody and how it functions. Then they determine sources of passive immunity and how HIV affects the immune system. Students also name defenses that the digestive system has against...
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Lesson Plan
Curated OER

Molecular Recognition and the Immune Response

For Teachers 8th - 10th
Students explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...
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Lesson Plan
Curated OER

Antibody and Antibody Specificity The Egg Mishap

For Teachers 10th - 12th
Students investigate a set of foods to find the presence of eggs after designing an experiment that will complete the test. They complete a test and discuss antibody-antigen specificity.
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Lesson Plan
Curated OER

A Pox No Longer Upon Us

For Teachers 10th
Tenth graders research the development and use of vaccines. They examine historical documents for qualitative observations and the basis of immunization. They examine primary and secondary immune responses as they relate to the...
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Worksheet
Curated OER

Blood

For Students 9th - 12th
In this blood worksheet, students complete a crossword puzzle given 24 clues about the components of the blood, the cells of the blood and the immune system with its antigens and antibodies found in the blood.
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Lesson Plan
Curated OER

Using Blood Tests to Identify Babies and Criminals

For Teachers 10th - 12th
Young scholars solve a crime by matching a suspect's blood type to physical evidence collected at the crime scene. In this forensic science instructional activity, students identify the different blood types. They explain how blood tests...
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Lesson Plan
Curated OER

The Genetics of Antibody Diversity

For Teachers 9th - 10th
Pupils distinguish between the light and heavy chain sections. For this biology lesson, students simulate the DNA splicing process. They calculate antibody diversity using the information given.
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Lesson Plan
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2
Children’s Hospital of Philadelphia

Development of Disease and Infection

For Teachers 9th - 12th Standards
It's all in the cards. Using cards to simulate a disease's attack on the immune system, pupils develop an understanding of how the immune system and pathogens react to each other and why at times the pathogen wins. Groups play a game to...
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Lesson Plan
Curated OER

Student Investigation on the Immune System and Hemeagglutination

For Teachers 11th - 12th
Students perform an experiment to demonstrate the principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. The materials to be used include antibodies from a rabbit that was...
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Lesson Plan
Curated OER

Multiple Alleles

For Teachers 10th - 12th
Students observe models of the ABO blood system including erythrocytes, antigens, and antibodies. They investigate the antigens that result from certain allele combinations and move antibodies to determine whether agglutination occurs...
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Worksheet
Curated OER

ABO Blood Types Worksheet

For Students 7th - 12th
Blood types and transfusions are explained in reading passages at the top of the worksheet. A chart of blood type compatibility is also provided. Biology students answer comprehension questions and then exercise critical-thinking skills...
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Handout
Ask A Biologist

Viral Attack

For Students 4th - 8th
Can you catch the same cold twice? Elementary and middle schoolers learn about what happens when a virus attacks their bodies, and how the immune system never forgets a virus, with an entertaining comic book. The packet includes...