Lesson Plan
TeachEngineering

Teach Engineering: Restriction Enzymes and Dna Fingerprinting

For Teachers 9th - 10th
The discovery of restriction enzymes and their applications in DNA analysis has proven to be essential for biologists and chemists. This lesson focuses on restriction enzymes and their applications to DNA analysis and DNA fingerprinting....
eBook
Khan Academy

Khan Academy: Restriction Enzymes & Dna Ligase

For Students 9th - 10th
Learn about restriction digestion, where the result has sticky ends and blunt ends. Also find out about ligation reactions.
eBook
Biology Pages

Kimball's Biology Pages: Restriction Enzymes

For Students 9th - 10th
This site is a retired biology professor's explanation of restriction enzymes. Good visual showing examples of how enzymes cut DNA to produce blunt or sticky ends.
Website
Other

Rebase: Restriction Enzyme Database

For Students 9th - 10th
Searchable database of restriction enzyme information. Must have more than basic knowledge of restriction enzymes.
Activity
TeachEngineering

Teach Engineering: Dna Forensics and Color Pigments

For Teachers 9th - 10th
Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint")...
Interactive
Cold Spring Harbor Laboratory

Dolan Dna Learning Center: Dna Restriction

For Students 9th - 10th
Animated slide show demonstrates the genetic engineering process of DNA restriction.
Interactive
John Wiley & Sons

Interactive Concepts in Biochemistry: Restriction Digestion/gel Electrophoresis

For Students 9th - 10th
Tutorial explains the processes of restriction digestion and gel electrophoresis and provides an interactive exercise to further your understanding.
Whiteboard
ClassFlow

Class Flow: Gel Electrophoresis & Restriction Mapping

For Teachers 9th - 10th
[Free Registration/Login Required] Following basic lab techniques of modern molecular biology, analyze the gel electrophoresis results of a restriction enzyme digest of DNA by using a HindIII-generated standard curve. Then solve two...
Website
Annenberg Foundation

Annenberg Learner: Applied Genetic Modification

For Students 9th - 10th
Explore practical uses of genetic engineering techniques to generate a plant that produces a hepatitis B protein for potential vaccine use. Examine the use of restriction enzymes for cloning and plasmid mapping.
Activity
Science Buddies

Science Buddies: Molecular Scissors

For Students 9th - 10th
Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change...
Website
The Franklin Institute

The Franklin Institute: Restriction Enzyme Cleavage

For Students 9th - 10th
A great step by step site for how DNA is prepared and plated in the process of electrophoresis.
Unit Plan
Annenberg Foundation

Annenberg Learner: Applied Genetic Modification

For Students 9th - 10th
Worldwide, millions of people are infected with the hepatitis B virus (HBV) and the world is in need of a resourceful and inexpensive vaccine. In this case study you will learn how to generate a plant that produces a hepatits B protein...
Handout
Other

North Dakota State: Central Dogma

For Students 9th - 10th
Information about how DNA is viewed in modern biology (it is at the center) and what its role is.
Activity
National Health Museum

Access Excellence: Dna Detectives

For Teachers 9th - 10th
A hands-on activity from Access Excellence for advanced biology classes. Students are given a crime scenario and three suspects. Their mission is to determine 'Who Dunnit?' by obtaining and analyzing DNA samples. Requires extensive...
Unknown Type
Khan Academy

Khan Academy: Recombinant Dna Technology

For Students 9th - 10th
Read a passage about recombinant DNA technology and answer the follow-up questions.
Unknown Type
Khan Academy

Khan Academy: The Detection of Myocardial Infarction

For Students 9th - 10th
Read this passage and study the graphic to complete a five-question quiz concerning the heart attack.

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