Curated OER
Transcription and Translation Lab Activity
Students investigate DNA strands. They study the sequence to determine if it is DNA or RNA and write the mRNA nucleotide sequence. After stringing the beads together to create the mRNA sequence they translate it into an amino acid...
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Secret Codes
Learners practice writing and decoding secret messages before discussing DNA and its role as a code for making proteins. They translate DNA into RNA and identify the sequence of amino acids to find a secret message. An interactive...
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Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
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How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
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Translating Genetic Information
Students explore the process of translation. They determine the correct sequencing and present their strands to the class. In addition, they compare normal red blood cells to sickle cells and complete discussion questions.
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How Is the Genetic Code Ultimately Translated Into a Protein?
Students examine the functions of mRNA, rRNA and tRNA. They explain the steps in the protein synthesis process. They practice using new vocabulary as well.
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Construction of a Hemoglobin Gene
Students see how eight pairs of triplets are equivalent to part of a gene and control a part of heredity. They comprehend how blood corpuscles manufacture normal hemoglobin. Students already comprehend that genes control the synthesis...
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All Aboard for Protein Synthesis
Fourth graders walk through the process of transcription and translation to demonstrate and explain protein synthesis. They utilize a worksheet imbedded in this plan to guide their role play.
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Why do we need Vitamin C in our diet? Or Why do we carry old inactive genes in our genome?
Students explore and explain how mutations in the DNA sequence of a gene may be silent or result in phenotypic change in an organism and in its offspring. They analyze how evolution and biodiversity are the result of genetic changes that...