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LABScI
DNA Structure: Gumdrop Modeling
DNA molecules hold the secrets that make us unique. The fourth of 12 lessons explores the structure of DNA by building candy models. After building the models, young scientists break their models to begin the process of DNA replication....
Curated OER
DNA Fingerprinting
Students study the process of DNA Fingerprinting and how DNA Fingerprinting is used in solving crimes. They examine a crime scenario that involves collecting DNA Fingerprinting information from blood collected at the crime scene. They...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Curated OER
Who Is It?/Who Done It?
Students conduct an experiment that allows them to assess individual differences in random DNA sequences and apply those differences when solving a forensic problem. After discussing the polymerase chain reaction and its use to identify...
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Curated OER
DNA Sequencing Simulation
Students simulate the Sanger method of DNA sequencing using color pop-beads as a representation of nucleotides and dideoxynucleotides. Students assemble DNA sequences and run their sequences through a "sequencing gel" and sketch what...
Curated OER
Macro-DNA: Doing DNA Fingerprinting
Students explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
Curated OER
Forensic Files: A DNA Dilemma
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Curated OER
DNA Fingerprinting
Students discuss DNA Fingerprinting and gel electrophoresis before participating in a crime solving activity. Students simulate their DNA using adding tape and complete the steps necessary to do a gel electrophoresis. They discuss the...
Curated OER
Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis
Pupils create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They compare...
Curated OER
Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
Curated OER
The Coding of Protein Molecules by DNA
Learners investigate the production of proteins by the DNA. In this protein synthesis lesson plan, students use paper models to explore transcription and translation to make proteins using DNA. Learners answer 10 questions to demonstrate...
Curated OER
Discovering DNA Structure
Students work in cooperative groups of four and manipulate paper nucleotides to discover the structure of DNA. They model DNA and sing the DNA song to review concepts. Lyrics to song included in lesson plan.
Curated OER
Comparison of Protein Sequences From Two Samples of Crabmeat Using Gel Electrophoresis As an Introduction To the Biotechnology Lab
Students discover that proteins that are the product of DNA translation are different for different species. They determine that by analyzing their mass and charge they can differentiate between two different species. They use some of...
Curated OER
DNA Blueprint for Life
Did you know that meat tenderizers contain DNA cutting enzimes? Did you know that you can isolate your own DNA? Or the DNA of fruit? Explore with your learners the DNA world with a series of experiments using readily available materials...
Curated OER
DNA Replication, Transcription, and Translation
Young scholars apply the rules of complementary base pairing to finding the complementary sequence to a given strand of DNA. After extensive researching, the also find the amino acid sequence encoded by a given strand of DNA.
Towson University
Chestnut Tree Lab
What will your class learn in a curious tale of a fungus, a virus, and a chestnut tree? Biology scholars discover the world of viral biocontrols through a DNA restriction lab. Groups research the decline of the American chestnut tree at...
Curated OER
Sequence Alignment
Young scholars explore the uses of sequence alignment. In this DNA lesson students complete several experiments on sequencing and algorithms.
Curated OER
Restriction Digest + DNA Comparison
Students compare different DNA and run a gel electrophoresis. In this DNA activity students complete a DNA activity that allows them to better understand its structure and function.
Curated OER
DNA Dry Lab
Young scholars use a DNA strand to identify the component parts. They discuss an RNA molecule, protein fragments, and nucleotides. They explore how the order of nucleotides determines the order of amino acids in proteins.
Curated OER
COMPARISON OF FOUR-, SIX-, AND EIGHT-bp CUTS IN CALF THYMUS DNA
Students use this laboratory exercise, restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. Assuming that the four component nucleotides (A, C, T, G) are distributed randomly within a DNA molecule, then any...
Curated OER
Building a DNA Molecule, Mitosis in Motion and Mutation Gossip
Students explore three lab experiments involving DNA, mitosis, and mutation. They complete activities and play games to review DNA, mitosis and mutation concepts. They build a DNA molecule and create flip cards representing mitosis in...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Curated OER
Pseudogene Suite
Students use Biology Workbench to explore DNA sequence data for the GULOP gene in humans, chimpanzees, orangutans, and crab-eating macaques and the beta globin gene and its pseduogene in humans, gorillas, and chimpanzees.