Lesson Plan
Curated OER

Creating an Enzyme-Substrate Model

For Teachers 9th - 12th
Learners explore the reaction rates of an enzyme-mediated reaction through experimentation. In small groups, they use everyday objects to demonstrate the effects of environmental variables on enzyme function. Students graph and...
Lesson Plan
Cornell University

Discovering Enzymes

For Teachers 6th - 12th
Explore the function of enzymes through a series of lab investigations. Learners use household enzymes such as hydrogen peroxide to model the role of enzymes. The enzymes break down proteins with and without a catalyst.
Lesson Plan
Curated OER

An Enzyme- Substrate Model

For Teachers 8th - Higher Ed
Students explore reaction rates of an enzyme-mediated reaction. They examine the effects of environmental variables on enzyme function. Students collect, graph, and analyze data relating to the reaction.
Lesson Plan
Curated OER

Enzyme Reaction Rates Using Toothpicks

For Teachers 10th - 12th
Students pretend to be enzyme that breaks toothpicks in timed intervals. They complete calculations to determine how many toothpicks are broken per second to determine the rate of reaction of the enzyme.
Lesson Plan
Curated OER

The Role of Enzymes

For Teachers 9th - 12th
Learners explore the role of enzymes in chemical reactions. In this enzymes lesson plan, students use hydrogen peroxide and manganese dioxide to observe a chemical reaction. Learners observe the rates of reactions of chalk, hamburger,...
Lesson Plan
Curated OER

Are Enzymes Specific for Their Substrates?

For Teachers 9th - 12th
Students discover enzyme to substrate specificity. The experiment uses samples of glucose and lactose in combination with the enzyme lactase. Students observe the reaction between the lactose and the lactase; the lack of a reaction...
Lesson Plan
Curated OER

Investigating Factors That Affect Rate of Enzyme Action

For Teachers 9th - 10th
Students explore the properties of enzymes. In this chemical reaction lesson plan, students explore enzymes through a Web-quest and investigative study. Students will collect and summarize data and create a class presentation. This...
Lesson Plan
Curated OER

Enzyme Action

For Teachers 9th - 10th
Students work with models of substrates and of enzymes and test the digestion of lactose with lactase. They determine if digestion of lactose has or has not occurred.
Lesson Plan
Curated OER

Cut-off Genes

For Teachers 9th - 12th
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Lesson Plan
Curated OER

Science Lesson: Chocolate Flavored Cherries

For Teachers 9th - 12th
Students are able to identify start and stop sequences in DNA. They are able to model using restriction enzyme and ligase to remove sections of DNA and reattach them. Students are introduced to the process of recombinat DNA through the...
Lesson Plan
Curated OER

Water-holding Capacity of Earth Materials

For Teachers 5th - 8th
Students design and conduct an experiment to test their ideas about how to speed up or slow down the rate of an enzyme-catalyzed reaction. They have access to an array of physical and chemical factors that might influence enzyme...
Lesson Plan
Cornell University

Who’s Got The Flu?

For Students 8th - 12th Standards
Become an immunologist for the day. Scholars elicit the use of the enzyme-linked immunoabsorbent assay (ELISA) to diagnose an infectious disease. Through the process, they learn about the immune system response to infectious diseases.
Lesson Plan
Cornell University

Extracting DNA

For Teachers 7th - 12th
Uncover the basics of DNA structure through exploration activities. Collaborative groups build DNA models and recreate the process of replication. Then, using plant cells such as peas or strawberries, they extract a DNA sample.
Lesson Plan
Curated OER

DNA Replication

For Teachers 9th - 10th
Learners create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Lesson Plan
Curated OER

Inquiry into Consumer Products

For Teachers 9th - 12th
Students recognize different consumer products, found in and around the home, that have reactive or denaturing properties when used together. They explore chemical and physical properties of each product by identifying chemical formulas...
Lesson Plan
Curated OER

Dinosaur and DNA Days

For Teachers 10th - 12th
Biology stars extract DNA samples from beef thymus and then examine its properties. They use enzymes to digest the DNA samples, and then use electrophoresis to separate fragments. Finally, they discuss methods and principles of...
Lesson Plan
Curated OER

Toothpick Breakdown

For Teachers 4th
Fourth graders model the activity of an enzyme acting on a substrate and observe relationships. Have students place toothpicks in a pile. One member of the team should break as many toothpicks as possible, in 10 seconds.
Lesson Plan
Curated OER

Enzymatic Reaction

For Teachers 6th - 12th
Students explore the effect enzymes have on reactions. They demonstrate the process of enzymatic reaction by making cheese. after experimentation, they answer a series of questions.
Lesson Plan
Curated OER

Transcription, Translation, and the Genetics of Microbes

For Teachers 11th - 12th
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
Lesson Plan
Curated OER

DNA Recombination II

For Teachers 9th - 10th
Students model recombination in DNA. They color the DNA sample and cut it out. Students use their "restriction enzymes" to cut the DNA into specific fragments. They separate the fragments using the "gel electrotrophoresis." Students...
Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting

For Teachers 9th - 11th
Young scholars explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
Lesson Plan
Curated OER

GenEng

For Teachers 7th - 9th
Students investigate the process of genetic engineering. In this genetic engineering lesson plan, students use paper models of DNA and plasmid bacterium to investigate the process of replicating DNA, splicing genes from DNA, and...
Lesson Plan
Curated OER

Genetic Engineering/Biotechnology

For Teachers 12th - Higher Ed
Students create a paper model of a plasmid and insert a DNA molecule that contains a specific gene into the plasmid. They complete an actual transformation involving E. coli bacterium and relate the two activities to one another.
Lesson Plan
Curated OER

P.L.E.P: Parts of Blood

For Teachers 6th - 8th
Students examine the different parts of blood.  In this human blood activity students work in groups and identify parts of blood and construct a model of human blood.