Lesson Plan
Curated OER

Determining Cutting Site Locations

For Teachers 7th - 12th
Students explore DNA restriction mapping. They cut pieces of paper into lengths representing those produced when specific enzymes are used to cut a strand of DNA.
Lesson Plan
Curated OER

Science Lesson: Chocolate Flavored Cherries

For Teachers 9th - 12th
Students are able to identify start and stop sequences in DNA. They are able to model using restriction enzyme and ligase to remove sections of DNA and reattach them. Students are introduced to the process of recombinat DNA through the...
Lesson Plan
Curated OER

Cut-off Genes

For Teachers 9th - 12th
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Lesson Plan
Curated OER

Simulation of Gene Splicing

For Teachers 9th - 12th
Students use the exercise as a prelude to a "wet" lab or as a substitute for such a lab. It correlates well with colony transformation labs. This lab is recommended for students what have difficulty with the abstractions that genetic...
Lesson Plan
Curated OER

Restriction Digest + DNA Comparison

For Teachers 9th - 12th
Students compare different DNA and run a gel electrophoresis.  In this DNA instructional activity students complete a DNA activity that allows them to better understand its structure and function. 
Lesson Plan
Curated OER

Molecular Explorations

For Teachers 9th - 12th
Students explain the processes for separating DNA from tissue and separating complex mixtures.  In this exploratory lesson students complete a lab where they extract DNA.  
Lesson Plan
Curated OER

Cracking the Code - Cloning Paper Plasmid

For Teachers 10th - 11th
Students explore the "genetic code." They observe how genes may be manipulated for genetic research, gene cloning, and genetic engineering. In a lab setting, students examine the mechanics involved in cutting and ligating DNAs into a...
Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting

For Teachers 9th - 11th
Young scholars explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
Lesson Plan
Curated OER

GenEng

For Teachers 7th - 9th
Students investigate the process of genetic engineering. In this genetic engineering lesson plan, students use paper models of DNA and plasmid bacterium to investigate the process of replicating DNA, splicing genes from DNA, and...
Lesson Plan
Curated OER

Genetic Engineering/Biotechnology

For Teachers 12th - Higher Ed
Students create a paper model of a plasmid and insert a DNA molecule that contains a specific gene into the plasmid. They complete an actual transformation involving E. coli bacterium and relate the two activities to one another.
Lesson Plan
Curated OER

Simulation of Gene Splicing

For Teachers 10th - 12th
Students simulate gene splicing by examining bacteria. They create a bacterial DNA into which they insert the human DNA (gene) that codes for growth hormone. They cut the sites of the enzyme to study how the human DNA can be joined to...
Lesson Plan
Curated OER

Genetics and Molecular Biology

For Teachers 9th - 10th
Pupils create DNA models using colored construction papers. In this biology lesson, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
Lesson Plan
Curated OER

Wolf Pack in a Bottle

For Teachers 9th - 12th
High schoolers participate in an activity of a mock electrophoresis using paper chromatography to study DNA and genetic restriction mapping.
Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis

For Teachers 10th - 12th
Students create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...