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Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Curated OER
DNA and Genetic Expression
Pupils, in groups, complete a worksheet on DNA transcription and translation. They determine codons for particular amino acids. They attempt to introduce mutations to determine what will happen to the DNA sequence.
Cold Spring Harbor Laboratory
Some DNA Does Not Encode Protein
Roy John Britten easily earned a PhD in nuclear physics—but he found painting with water colors too difficult. Young scientists learn about Britten's life, career, and research with an online interactive. They read a biography, view...
Pearson
Transcription
Teach young biologists the language of life with this series of worksheets on DNA. By working through these pages, students expand their understanding of genetics as they learn about the process of transcription and the...
Curated OER
Using Amino Acid Sequences to Show Evolutionary Relationships
Compare protein fragments, count amino acids, and use the information to explore common ancestry. The resource mentions a student worksheet, however, a separate printable worksheet is not provided. The exercises are written into the...
Cold Spring Harbor Laboratory
DNA Responds to Signals from Outside the Cell
How do cells know when to replicate, transcribe, and stop? James E. Darnell, Jr. shifted from studying medicine to biochemistry and decided to address this mystery. Learn about his research, discoveries, and the impact on future medical...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Curated OER
Restriction Enzymes
Students explore enzymes and enzyme combinations. They examine and cut up and practice matching DNA sequences.
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Curated OER
Gene Action and Mutation
Students review terms related to DNA structure and function. They complete a variety of worksheets in small groups or in pairs reflecting the unit's concepts regarding DNA. They submit their worksheets for grading.
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Curated OER
How Cells Reproduce
Students explain why cells reproduce and draw a diagram of each of the stages in mitosis. They put the stages of mitosis (interphase, prophase, metaphase, anaphase, telophase, and cytokinesis) in the correct sequence, from the beginning...
Curated OER
Fractals Rock
Young scholars identify the repeated sequences of a pattern. In this geometry lesson, students identify fractals in patterns and nature. They construct a fractal tree and make conjectures.
Curated OER
Fractals Rock: Investing the Fractal Tree
Students investigate the relationship between fractals and sequences. In this geometry lesson, students build a fractal tree. They investigate different career fields where fractals are used in the real world.
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Curated OER
Punnett Squares/Genetics
Ninth graders complete a monohybrid cross and a dihybrid cross. In this biology lesson, 9th graders predict the traits of offspring using the Punnett square. They differentiate recessive and dominant genes.