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Curated OER
The Watson-Crick Model of DNA Structure
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Concord Consortium
DNA: The Double Helix
Picture a double helix as a twisted ladder. Scholars see this image through a simulation that allows young scientists to observe a small fragment of DNA in many different formats. They compare the models, colors, bonds, and strands as...
Curated OER
DNA Detectives
In order to understand DNA fingerprinting, advanced biology aces divise a crime scenario and analyze three different samples of lambda DNA. This creative lesson plan provides practice with micropipettes, electrophoresis boxes, and other...
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Chemistry Collective
Virtual Lab: DNA Binding Problem
Why do the bases in DNA pair up the way they do? Unravel the mystery of the double helix in a virtual lab. Young scientists follow in the footsteps of Watson and Crick to determine the free energy associated with DNA base pair binding....
Howard Hughes Medical Institute
Niche Partitioning and DNA Metabarcoding
What is DNA metabarcoding? Show your biology class the latest method for studying biodiversity in an ecosystem with a fun, informative interactive. Individuals examine the animal species that compete for vegetation, then learn how their...
Curated OER
Forensic Files: A DNA Dilemma
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Gene Jury
DNA Detectives
Police find a man murdered in a local hotel, DNA everywhere, and now they need scholars' help. Budding detectives step into a crime scene playing the roles of victim, suspects, and investigators. They apply knowledge of criminology and...
Chemistry Collective
Virtual Lab: DNA - Dye Binding: Equilibrium and Buffer Solutions
Your class is bound to be fascinated by this virtual lab! Young biochemists explore molecules that bind to specific sites on the DNA molecule through a skillful simulation. The lesson challenges learners to create a DNA-bound solution...
Concord Consortium
DNA to Protein
Starting from a view of cells, a constructive simulation shows every step of building a new protein. It walks through transcription, translation, building amino acids, and folding the protein. Viewers control if it plays as a video or...
Curated OER
The Structure of DNA
Students describe the structure of the double helix, explain how DNA copies itself, and recognize that the sequence of DNA is what makes each individual unique.
Curated OER
DNA Sequencing Simulation
Students explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
DNA Modeling
Young scholars study DNA and its nucleotides. They manipulate paper nucleotides of DNA and investigate how the molecule is produced. Paper versions of sugars, phosphates, and nitrogen bases included.
Curated OER
lambda DNA Fingerprinting Simulation
Students perform restriction digests on DNA samples from four individuals, and then search for similarities between the individuals by running the restriction fragments on an electrophoresis gel.
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Curated OER
DNA Chips
Students discover what they need to know about DNA chips. They extend this knowledge to analyze gene expression data to diagnose two kinds of leukemia.
Curated OER
The ABC's of DNA
Students describe genetics as if they were explaining it to a young child. After reading an article, they discover new discoveries in the human genome project. Using the internet, they research a pair of genetic terms and develop a...
Curated OER
My Science Box: DNA Fingerprinting
Students identify DNA in a crime scenario. In this DNA lesson, students perform paper chromatography and compare it against the pens of various suspects.
Curated OER
Where's the CAT? a DNA Profiling Simulation.
Students explore DNA technology. Students participate in a simulation to perform at the basic steps of a DNA profile. They observe copies of DNA sequences, construct DNA probes, and discuss outcomes of their experiment.
Curated OER
Life Science: DNA Whodunit?
Young scholars role play an honorary detective to assist in solving a crime committed. They investigate by a bank robbery and interview eyewitnesses using their Crime Investigation Notebook and clues from an eyewitness account from the...
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