Paul Andersen explains how DNA replication ensures that each cell formed during the cell cycle has an exact copy of the DNA. He describes the Meselson-Stahl experiment and how it showed that DNA copies itself through a semi-conservative...

Mismatch repair (MMR) is a DNA repair mechanism that corrects base-pairing errors and small insertions or deletions that escape proofreading during DNA replication. A protein complex identifies the mismatch, excises a section of the...

DNA repair mechanisms like base excision repair (BER) and nucleotide excision repair (NER) fix damage by removing and replacing affected regions. BER removes a single damaged base using glycosylases (e.g., to fix deaminated cytosine),...

Restriction Enzyme Set: 3. This clip shows how restriction enzymes are used to produce recombinant DNA.

Restriction Enzyme Set: 2. This clip explains the way in which enzymes clip DNA at specific points. The value of restriction enzymes in DNA is presented.

Here we have provided an explanation of lagging strand DNA replication followed by an great animation beginning at 4:04.