Our DNA holds thousands of dead genes and we’ve only just begun to unravel their stories. But one thing is already clear: we’re not just defined by the genes that we’ve gained over the course of our evolution, but also by the genes that...

It was recently brought to our attention that there's a category here that we have covered quite a lot, and that people have… watched. Here's a selection of our absolute favorite SciShow Pee episodes!

It’s kind of a pain to get out of the pool just to use the bathroom, plus chlorine is a disinfectant so it is fine to pee in the pool, right? Well, it turns out that might give you some health issues.

It was recently brought to our attention that there's a category here that we have covered quite a lot, and that people have… watched. Here's a selection of our absolute favorite SciShow Pee episodes!

The SciShow Talk Show has a new look! And a new guest who isn't new at all - Jessi Knudsen Castañeda from Animal Wonders joins Hank to talk about one of her favorite subjects: poop! They are joined by Augusto Castañeda and Yucca the...

Summer is coming to a close, but there is still time to take a cool, refreshing dip in the water of your choice. Before you do, be sure to check out this swimming compilation to get answers to all the questions you didn’t even know you...

Hank takes us on the fascinating journey through our excretory system to learn how our kidneys make pee.

The biggest kidney stone on record weighed more than a kilogram and was 17 centimeters in diameter. The patient didn't actually swallow a stone the size of a coconut; kidney stones form inside the body. So how do they grow in the first...

We've been talking about animals in the context of ecology, so let's continue and examine water balance, as well as photoperiods. How do animals regulate water intake? How do they excrete waste? How do they interact with sunlight? Let's...

Jessi brings you a fun compilation of fascinating facts about animals! How do frogs swallow? Why don't duck's feet freeze on ice? Can owls turn their head ALL the way around? Find out answers to these questions, and more!

Jessi shares 5 ways to tell if your bird might be sick. Featuring lots of the birds at Animal Wonders (that aren't sick, just happy to join in the fun of the day)

Jessi features four fun facts about feces and how some animals use their poop to help them survive.

Nucleotide Metabolism | Degradation of Uric Acid

Purine Catabolism: Conversion of Hypoxanthine to Uric Acid

In this video, we do an introduction to gout by discussing purine degradation, uric acid production, and hyperuricemia. We also discuss why uric acid is not degraded further in humans by looking at the biochemistry.

Vitamin C: Metabolism and Function

Thymine Catabolism

Best & Worst Foods to Eat with Gout | Reduce Risk of Gout Attacks and Hyperuricemia



Gout is an inflammatory monoarticular arthropathy that is caused by monosodium urate crystal deposition within particular joints in the body....

Here, we explore the biosynthetic pathway for vitamin C (ascorbic acid) from glucuronic acid. Also, we explore inability of some organisms (e.g., humans) to perform this biosynthesis due to the GULO pseudogene.

Urate Oxidase and Urate (Part 3): Why Do Humans and Other Apes Live Longer?

Urate Oxidase and Urate (Part 2): Physiology, Gout, and Kidney Stones

Urate Oxidase and Urate (Part 1): Physiology, Biochemistry, and Mechanism

Nucleotide Metabolism | Degradation of IMP, AMP, & GMP

In this video, we explore the mechanism of allopurinol, a drug used in the treatment of gouty arthritis.