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The Cytochrome-C Lab
Students examine a method biologists use to try to determine relationships. They examine how amino acid sequences have been determined for a number of proteins, and how scientists can make inferences about DNA based on the amino acid...
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Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
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Molecular Evidence for Evolutionary Relationships
Students compare the amino acid sequences in cytochrome-c for a variety of organisms and use this information to infer evolutionary relationships. Students investigate the role of homeobox genes and what this indicates about the...
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DNA Dry Lab
Students use a DNA strand to identify the component parts. They discuss an RNA molecule, protein fragments, and nucleotides. They explore how the order of nucleotides determines the order of amino acids in proteins.
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Secret Codes
Students practice writing and decoding secret messages before discussing DNA and its role as a code for making proteins. They translate DNA into RNA and identify the sequence of amino acids to find a secret message. An interactive...
Science 4 Inquiry
The Monster Mash
Young scientists create monsters by applying their knowledge of transcription and translation. They randomly find the DNA, assign it a codon, and build monsters piece by piece.
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Who is the Sea Otter Related to?
Students examine the genetic relationships of different organisms. In groups, they discover the importance of genes and how different amino acids show various evolutionary relationships. They use an online database to continue their...
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DNA and Protein Synthesis
Tenth graders work with a partner, and copies of the attached worksheet "Amino Acid Codon Table" They discuss ways an organism, obtains and uses proteins. Students view a teacher prepared DNA strand banner, and record the complementary...
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SAY IT WITH DNA: Protein Synthesis Tutorial
Ninth graders explore protein synthesis. In this DNA lesson students complete a worksheet and a DNA lab activity.
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Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
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Molecular Biology and Primate Phylogenetics
Pairs of high school biologists compare amino acid differences in the beta hemoglobin of different primates. They use the information collected to construct a phylogenic tree. Follow-up discussion questions are provided. This is a...
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Catalase: A Bioinformatics Case Study
Students investigate the physical structure of a protein by using a computer simulation tool. They record its primary amino acid structure while viewing it in three dimensions for a better visual recognition. There is also a comparison...
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DNA Coloring - Transcription and Translation
For this DNA worksheet, students review the transcription and translation processes. Students label and color the different parts of a DNA strand. This worksheet has 7 fill in the blank questions.
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DNA and Genetic Expression
Students, in groups, complete a worksheet on DNA transcription and translation. They determine codons for particular amino acids. They attempt to introduce mutations to determine what will happen to the DNA sequence.
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The Spanish Omelet
High schoolers use analogies to show the relationships among cell, nucleus, genes, chromosome, ribosome, replication, mitosis, transcription, translation, DNA, RNA, amino acids and proteins, genotype, phenotype, and genetics vs....
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Discovering DNA Structure
Students work in cooperative groups of four and manipulate paper nucleotides to discover the structure of DNA. They model DNA and sing the DNA song to review concepts. Lyrics to song included in lesson plan.
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Whose DNA Is That?
Students investigate the use of technology in order to identify different sequences of amino acids by using online web tools. They enhance problem solving skills with amino acid identification skills and strengthening comfort with using...
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The Coding of Protein Molecules by DNA
Students investigate the production of proteins by the DNA. In this protein synthesis lesson plan, students use paper models to explore transcription and translation to make proteins using DNA. Students answer 10 questions to demonstrate...
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Lesson on Proteins
Students examine the importance of proteins including their function and structure. In this protein instructional activity students play a game to help them better understand proteins.
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How Mutations Lead to Changes in Cell Structure and Function
Students investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare...
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Genetic Jewels: Building the DNA Model
Students construct segments of DNA to create a piece of jewelry. In this genetics lesson students create a DNA sequence that they turn into something to wear.
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Pseudogene Suite
Learners use Biology Workbench to explore DNA sequence data for the GULOP gene in humans, chimpanzees, orangutans, and crab-eating macaques and the beta globin gene and its pseduogene in humans, gorillas, and chimpanzees.
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Protein Factory
Learners examine protein synthesis and how DNA is transcribed. In this investigative instructional activity students play a role in the messenger RNA when it creates nucleotides.
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Protein Synthesis
In this science related worksheet, pupils study, locate and answer ten multiple choice questions dealing with protein synthesis.