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Lesson Plan
Curated OER

Antibodies and Antigens: Fitting Together

For Teachers 8th - 10th
Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require students to explain in writing how each antibody works...
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Lesson Plan
Curated OER

Antibodies

For Teachers 9th - 12th
Students conduct a series of exploration activity on how vaccines and antibodies work. In this biology instructional activity, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting...
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Lesson Plan
Curated OER

Antigens versus Antibodies "KO'd in Round Three" The Third Line of Defense of the Human Immune System

For Teachers 7th
Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.
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Lesson Plan
Curated OER

Antigens

For Teachers 8th - 12th
Students examine antigens including ones found in humans.  In this immune lesson students complete several experiments in relation to antigens and antibodies.
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Lesson Plan
Curated OER

Disease Diagnosis

For Teachers 9th - 12th
Learners comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...
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Lesson Plan
Curated OER

Teaching Multiple Alleles

For Teachers 9th - 12th
Students view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...
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Lesson Plan
Curated OER

Operation Anitbody

For Teachers 9th - 12th
Students identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case studies,...
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Lesson Plan
Curated OER

Molecular Recognition and the Immune Response

For Teachers 8th - 10th
Students explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...
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Lesson Plan
Curated OER

Antibody and Antibody Specificity The Egg Mishap

For Teachers 10th - 12th
Students investigate a set of foods to find the presence of eggs after designing an experiment that will complete the test. They complete a test and discuss antibody-antigen specificity.
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Lesson Plan
Curated OER

A Pox No Longer Upon Us

For Teachers 10th
Tenth graders research the development and use of vaccines. They examine historical documents for qualitative observations and the basis of immunization. They examine primary and secondary immune responses as they relate to the...
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Lesson Plan
Curated OER

Using Blood Tests to Identify Babies and Criminals

For Teachers 10th - 12th
Students solve a crime by matching a suspect's blood type to physical evidence collected at the crime scene. For this forensic science lesson, students identify the different blood types. They explain how blood tests work.
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Lesson Plan
Curated OER

The Genetics of Antibody Diversity

For Teachers 9th - 10th
Students distinguish between the light and heavy chain sections. In this biology lesson, students simulate the DNA splicing process. They calculate antibody diversity using the information given.
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Lesson Plan
2
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Children’s Hospital of Philadelphia

Development of Disease and Infection

For Teachers 9th - 12th Standards
It's all in the cards. Using cards to simulate a disease's attack on the immune system, pupils develop an understanding of how the immune system and pathogens react to each other and why at times the pathogen wins. Groups play a game to...
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Lesson Plan
Curated OER

Student Investigation on the Immune System and Hemeagglutination

For Teachers 11th - 12th
Students perform an experiment to demonstrate the principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. The materials to be used include antibodies from a rabbit that was...
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Lesson Plan
Curated OER

Multiple Alleles

For Teachers 10th - 12th
Students observe models of the ABO blood system including erythrocytes, antigens, and antibodies. They investigate the antigens that result from certain allele combinations and move antibodies to determine whether agglutination occurs...
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Lesson Plan
2
2
Children’s Hospital of Philadelphia

The Adaptive Immune System

For Teachers 9th - 12th Standards
Attack the pathogen from within. Learners delve deeper into the immune system and find out about the adaptive immune system such as T and B cells. Groups create graphical models of the adaptive immune system along with a multimedia...
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Lesson Plan
Curated OER

Food Forensics: A Case of Mistaken Identity

For Teachers 9th - 12th
Students develop an experiment to test a hypothesis. They use their knowledge of antigen-antibody specificity to develop a hypothesis. Students articulate that the antibody-antigen specificity is one part of the immune system. They...
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Lesson Plan
Curated OER

Common Vaccinations

For Teachers 6th - 8th
Students examine vaccinations and how they work.  In this vaccinations lesson students create posters that describe the various types of vaccines. 
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Lesson Plan
Curated OER

Body Battles!

For Teachers 7th
Seventh graders explain the role of white blood cells in fighting infections. In this life science lesson, 7th graders create flow charts showing the immune response process. They act out and play a game to simulate actions of the immune...
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Lesson Plan
Curated OER

Food Forensics: A Case of Mistaken Identity

For Teachers 9th
Ninth graders explore the specific reaction between an antigen and the antibody that recognizes it. They carry out an exploratory experiment leading to the concept of specificity.
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Lesson Plan
Curated OER

Pre-Hardy-Weinberg

For Teachers 6th - 10th
Students examine the inheritance of ABO blood groups.  In this investigative lesson students perform a lab and show how natural selection can alter the gene frequencies in a population.
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Lesson Plan
Curated OER

Anatomy and Physiology Study Questions on Immunology

For Teachers 12th - Higher Ed
In this anatomy and physiology study question worksheet, students define 20 terms related to the immune system. They answer 19 short answer questions that deal with immunology, autoimmune diseases, and the components and cells related to...
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Lesson Plan
Curated OER

Fighting Infection

For Teachers 6th - 8th
Middle schoolers study immune responses and the structures that are related to immune cells functions.  For this fighting infection lesson students construct antibody complexes and model the interaction of the immune system when it is...
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Lesson Plan
Cornell University

Who’s Got The Flu?

For Students 8th - 12th Standards
Become an immunologist for the day. Scholars elicit the use of the enzyme-linked immunoabsorbent assay (ELISA) to diagnose an infectious disease. Through the process, they learn about the immune system response to infectious diseases.