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Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Concord Consortium
Concord Consortium: Stem Resources: Dna to Protein
Investigate how the genetic code on a DNA strands controls what protein is produced with this collection of animations and 3D models. Explore an interactive 3D model of the double helix, watch an animation of transcription, and see the...
Science Buddies
Science Buddies: Project Ideas: Dna Damage: Ultraviolet Rays and Yeast Colonies
In this biotechnology science fair project, investigate how DNA damage affects growth of yeast that are DNA-repair deficient. The Science Buddies project ideas are set up consistently beginning with an abstract, objective, and...
Science Buddies
Science Buddies: What Is the Woolly Mammoth's Closest Living Relative?
Although Woolly Mammoths have been extinct for thousands of years, scientists continue to learn more and more about this mighty animal. Some of the most exciting new research is being produced by looking at DNA extracted from the hair...
National Health Museum
Access Excellence: Dna Dry Lab
This lab illustrates how the order of nucleotides in DNA determines the order of amino acids in proteins. Relates DNA function to that of RNAand provides an exercise to demonstrate how mutations may occur. Includes a lesson plan and...
National Health Museum
Access Excellence: Genes, Dna, and Mutations
A good Access Excellence site with an introduction to the processes of transcription and translation, leading to a student modeling activity.
Science Buddies
Science Buddies: What Duration of Ultraviolet Exposure Kills Bacteria?
Ultraviolet light can damage DNA molecules. If a cell's DNA repair mechanisms can't keep up with the damage, mutations are the result. As harmful mutations accumulate, the cell eventually dies. How much ultraviolet light is too much for...
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