Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
Development Balances Cell Growth and Death
Cells demonstrate a life cycle like other living things, but what if death was no longer part of the cycle? Learn about the important balance requiring death to continue functioning. An online interactive introduces a group of scientists...
Cold Spring Harbor Laboratory
Different Genes Are Active in Different Kinds of Cells
Personalized medicine prevents many trial-and-error scenarios when time counts the most. Learn how gene expression and screening genomes improves health outcomes in cancer patients, those with auto-immune disorders, and more. An online...
Cold Spring Harbor Laboratory
Genes Can Be Turned On and Off
Regulations exist in many places from business to schools, but what about in our genes? Learn about gene regulation with an online interactive. It uses an animation to introduce the topic, many photographs of the scientists best known...
Cold Spring Harbor Laboratory
Some DNA Can Jump
Some people have a natural ability to jump, but did you know DNA also naturally jumps? Learn about the fun habit by looking at the research of a pioneering female scientist. Barbara McClintock fought prejudice and surpassed her mentors...
Cold Spring Harbor Laboratory
Some DNA Does Not Encode Protein
Roy John Britten easily earned a PhD in nuclear physics—but he found painting with water colors too difficult. Young scientists learn about Britten's life, career, and research with an online interactive. They read a biography, view...
Cold Spring Harbor Laboratory
DNA Is Packaged in a Chromosome
Roger Kornberg, the oldest son of two biochemists, won the 2006 Nobel Prize in Chemistry. Learn about Kornberg and his scientific research with an animation, videos, biography, and an applied problem-solving activity. A summary and...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Cold Spring Harbor Laboratory
RNA Was the First Genetic Molecule
Can organic molecules come from a pre-biotic environment? Stanley Lloyd Miller proved it is possible when exactly the right conditions exist. Learn about his experiment and the other experiments later building off of it that changed the...
Cold Spring Harbor Laboratory
Some Viruses Store Genetic Information in RNA
Can a high school program alter the entire course of your life? David Baltimore and Howard Temin participated in high school programs working in research laboratories and went on to win the 1975 Nobel Prize. Learn about these two...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Cold Spring Harbor Laboratory
DNA Responds to Signals from Outside the Cell
How do cells know when to replicate, transcribe, and stop? James E. Darnell, Jr. shifted from studying medicine to biochemistry and decided to address this mystery. Learn about his research, discoveries, and the impact on future medical...
Cold Spring Harbor Laboratory
Higher Cells Incorporate an Ancient Chromosome
Chromosomes contain keys to history including links from royalty to Neanderthals. Young scientists learn about Ivan Wallin's research into chromosomes with an animation and videos. Then, the concept connects to mysteries related to...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Cold Spring Harbor Laboratory
Genes Get Shuffled When Chromosomes Exchange Pieces
Some genes link to others that have implications for inheritance. A set of resources lead pupils through the history of this discovery. They explain how chromosomes recombine and which parts are more susceptible to this linkage....
Cold Spring Harbor Laboratory
Chromosomes Carry Genes
Some traits only exist in males and some only in females. Pupils learn how the location of genes on sex chromosomes determines them using an interactive lesson. An animation illustrates how scientists know this to be true and shows how...
Cold Spring Harbor Laboratory
A Gene Is Made of DNA
Does a protein or DNA store genetic instructions for life? Follow the research from the 1920's experiments on mice through the 1940's experiments on bacteria to learn the answer to the difficult question. Scholars use an online...
Cold Spring Harbor Laboratory
Evolution Begins with the Inheritance of Gene Variations
Connect Mendelian genetics with Darwinian theories. An interactive lesson lets pupils explore how George Shull used research from other scientists to explore genetic variation. The resource outlines the statistical analysis of genetic...
Cold Spring Harbor Laboratory
Specialized Chromosomes Determine Gender
Are you an XX or an XY? Budding scientists learn about cellular fertilization and the determination of gender in a thorough online lesson. They follow their study with a set of interactive reflection questions.
Cold Spring Harbor Laboratory
Sex Cells Have One Set of Chromosomes; Body Cells Have Two
What's the difference between body cells and sex cells? Learners explore the question and the process of meiosis using an interactive lesson. An animation describes the discovery of meiosis and describes its phases for a detailed and...