Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics

People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell disease, sickle cell trait, and malaria protection. They apply their understanding to genetic counseling and perform statistical analysis.

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CCSS: Designed
NGSS: Designed
Instructional Ideas

  • Worksheets work best as independent work for college level courses and as small group work for high school level courses
Classroom Considerations

  • Assumes pupils previously viewed a short film
  • Relies on prior knowledge of genotype, phenotype, homozygous, heterozygous, dominance, codominance, probability, pedigrees, inheritance, and chi-square analysis
Pros

  • Includes many real-life situations
  • Provides an answer key
Cons

  • None