Fred Sanger created the first method of sequencing DNA in 1977 using chemical alterations. Learn more about the Sanger method with a brief animation demonstrating the replication, ordering, and piecing together steps in the process.

Concepts

dna, dna sequence

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Additional Tags

science

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Instructional Ideas

• After watching the video, have pupils describe, in their own words, how DNA is sequenced
• Discuss in more detail the chemical alterations performed on the DNA

Classroom Considerations

• Assumes prior knowledge of DNA and the four bases

Pros

• Requires very little class time to share
• Includes a transcript for the hearing impaired

Cons

• None

Common Core

SL.9-10.2 SL.11-12.2 RST.9-10.4 RST.11-12.4