Finally, something that is better when it's broken! Computers make sequencing short pieces of genome an easy task, yet they struggle with long sequences. Learn about one method for sequencing genomes by breaking it into smaller pieces and then reassembling. An understanding of the limits and challenges of this method provide an opening for future technology.

Concepts

genomes, dna sequence

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Additional Tags

science

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Instructional Ideas

• Challenge students to create a better analogy for the process than a shotgun

Classroom Considerations

• Relies on prior knowledge of DNA sequencing
• Allows for downloading in MOV and WMV formats

Pros

• Works well in traditional or flipped classes
• Includes closed captioning for the hearing impaired

Cons

• None

Common Core

SL.9-10.2 SL.11-12.2 RST.9-10.4 RST.11-12.4