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Determining Cutting Site Locations
Students explore DNA restriction mapping. They cut pieces of paper into lengths representing those produced when specific enzymes are used to cut a strand of DNA.
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Science Lesson: Chocolate Flavored Cherries
Students are able to identify start and stop sequences in DNA. They are able to model using restriction enzyme and ligase to remove sections of DNA and reattach them. Students are introduced to the process of recombinat DNA through the...
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Who Ate The Cheese?!
In this crime scene investigation worksheet, students simulate DNA sequencing and DNA restriction analysis using paper strips of DNA. Students compare the crime scene DNA to the suspects and determine who is guilty.
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Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands." Modeling...
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Simulation of Gene Splicing
Students use the exercise as a prelude to a "wet" lab or as a substitute for such a lab. It correlates well with colony transformation labs. This lab is recommended for students what have difficulty with the abstractions that genetic...
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DNA Fingerprinting with Restriction Enzymes
Students will illustrate how restriction enzymes work by piecing together parts of a puzzle. Then they apply this knowledge to help them analyze genetic evidence from the scene of a crime as well as to help them comprehend how a DNA...
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Restriction Digest + DNA Comparison
Students compare different DNA and run a gel electrophoresis. In this DNA lesson students complete a DNA activity that allows them to better understand its structure and function.
Teach Engineering
DNA Forensics and Color Pigments
Use food coloring in electrophoresis. The last segment in a four-part series mimics DNA fingerprinting by using chromatography. Teams conduct chromatography on food coloring to find colors that use similar pigmentation in their makeup.
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Molecular Explorations
Students explain the processes for separating DNA from tissue and separating complex mixtures. In this exploratory lesson students complete a lab where they extract DNA.
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DNA Race Track
Twelfth graders simulate a DNA fragment running through a gel electrophoresis in a class activity. Students work in teams as a DNA sample with each person on the team representing a fragment that moves through the gel at a specific speed.
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Cracking the Code - Cloning Paper Plasmid
Students explore the "genetic code." They observe how genes may be manipulated for genetic research, gene cloning, and genetic engineering. In a lab setting, students examine the mechanics involved in cutting and ligating DNAs into a...
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Macro-DNA: Doing DNA Fingerprinting
Students explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
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GenEng
Students investigate the process of genetic engineering. In this genetic engineering lesson plan, students use paper models of DNA and plasmid bacterium to investigate the process of replicating DNA, splicing genes from DNA, and...
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Outbreak! Electrophoresis: Where the Bands Are
Students examine why pieces of DNA move at different rates and over different distances. For this DNA lesson students complete an activity.
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Genetic Engineering/Biotechnology
Students create a paper model of a plasmid and insert a DNA molecule that contains a specific gene into the plasmid. They complete an actual transformation involving E. coli bacterium and relate the two activities to one another.
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Simulation of Gene Splicing
Students simulate gene splicing by examining bacteria. They create a bacterial DNA into which they insert the human DNA (gene) that codes for growth hormone. They cut the sites of the enzyme to study how the human DNA can be joined to...
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Genetics and Molecular Biology
Students create DNA models using colored construction papers. In this biology activity, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
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How to Conquer a Genetic Disease
Students study the details of DNA restriction analysis and how RFLP's are used to locate genes on a map of DNA.
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Wolf Pack in a Bottle
Students participate in an activity of a mock electrophoresis using paper chromatography to study DNA and genetic restriction mapping.
Kenan Fellows
Unit 2: DNA Analysis
Ever wonder how they solve those mysterious murders in TV crime dramas? The second of four units in a Biotechnology series introduces scholars to the many methods of DNA analysis. Pupils create and run their own gel electrophoresis...
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A Little More Advanced Biotechnology Tools: Better Plasmids
A nice set of information that will help your students understand the process of using recombinant plasmids. DNA hybridization and blotting mechanisms help illustrate expressed genes and the concepts behind the Human Genome Library....
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A Little More Advanced Biotechnology Tools; Better Plasmids
After using this DNA and plasmids slide show, the steps of the delicate procedures of southern blotting and DNA libraries should be more clear to your students. Students will read the guidelines and are also prompted to answer questions...
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Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis
Young scholars create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...
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DNA Fingerprinting Simulation
In this DNA fingerprinting simulation instructional activity, students perform an activity that represents using a gel electrophoresis. Students decide who commits a crime in a forensics style lab.