Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection in Humans
Sickle cell disease only occurs when both parents contribute the trait, and mostly in those of African descent. Where did it come from? How did it evolve? Tony Allison, a molecular biologist, noticed a connection between sickle cell and...
Howard Hughes Medical Institute
Testing a Hypothesis
Are sickle cell disease and malaria related somehow? Scholars learn about both illnesses and the hypotheses that they are related. They discuss, view a video, and answer questions to demonstrate understanding. The resource includes an...
Howard Hughes Medical Institute
How Do Fibers Form?
The proteins inside a cell determine the shape of the cell. While most red blood cells have a circular shape, those with sickle cell take the shape of a sickle. This change in shape causes multiple issues in the system. Scholars solve...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Curated OER
Allele Frequencies and Sickle Cell Anemia Lab
Pupils investigate how selective forces like food, predation and diseases affect evolution. In this genetics lesson, students use red and white beans to simulate the effect of malaria on allele frequencies. They analyze data collected...
Howard Hughes Medical Institute
A Lesson on the Nature of Science
If you are looking for a great way to present natural selection in humans, look no further. This handout is intended to accompany the 14-minute video The Making of the Fittest: Natural Selection in Humans, which can be found on the...
Biology Junction
Population Genetics
Genetic variation shows the health of a population, yet cheetahs show very little variation over that last 10,000 years. Scholars learn the importance of genetic variation in populations after viewing an informative presentation. It...
Howard Hughes Medical Institute
A Lesson on the Nature of Science
If you are looking for a great way to present natural selection in humans, look no further. This handout is intended to accompany the 14-minute video The Making of the Fittest: Natural Selection in Humans, which can be found on the...
Curated OER
Measuring Evolution of Populations
The Hardy-Weinberg principle is the focus of this concise slideshow. Some vocabulary definitions are given on the first 2 slides, and the rest are given over to examples of the Hardy-Weinberg theorem. Calculations of the H-W principle...
Howard Hughes Medical Institute
Population Genetics, Selection, and Evolution
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
Curated OER
Measuring Evolution of Populations
The five agents of evolutionary change are reviewed in this slideshow. Definitions of common terms involved with populations and equilibrium are given, and there are some presentations of Hardy Weinberg equations for common examples of...
Curated OER
Antibodies and the Immune Response Lesson Plans - Biology Teaching Thesis
High schoolers are introduced to bacteria and their role in biology and finishes with a lab experiment that focuses on antibiotics. They are given an overview of the important concepts involving bacteria and their potential resistance to...
Curated OER
Chapter Fourteen Questions: Human Genome
This multiple-choice and short-answer quiz covers chromosomes, genetic disorders, and more. The multiple choice section could work as a pretest, as well.
Curated OER
Genetic Disorders with Cultural Roots: International Insects
Pupils recognize that certain populations have specific genetic disorders that could benefit or harm them in their environment, work out punnett square problems and infer offspring probabilities from results, and provide advantages and...