Activity
Howard Hughes Medical Institute

Molecular Genetics of Color Mutations in Rock Pocket Mice

For Teachers 9th - 12th Standards
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Activity
Howard Hughes Medical Institute

Biochemistry and Cell Signaling Pathway of the Mc1r Gene

For Teachers 9th - 12th Standards
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Activity
Howard Hughes Medical Institute

Natural Selection and Evolution of Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Activity
Howard Hughes Medical Institute

The Molecular Evolution of Gene Birth and Death

For Teachers 9th - 12th Standards
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Activity
Howard Hughes Medical Institute

Population Genetics, Selection, and Evolution

For Teachers 9th - 12th Standards
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
Activity
Howard Hughes Medical Institute

Weighing the Evidence for a Mass Extinction Part 2: On Land

For Teachers 6th - 12th Standards
What can fossils tell us about periods of extinction? Young scholars interpret fossil layers to make conclusions about changes in life during different geological time periods. They analyze the fossils for abundance and diversity as well...
Interactive
Cold Spring Harbor Laboratory

Genes Get Shuffled When Chromosomes Exchange Pieces

For Students 9th - 12th Standards
Some genes link to others that have implications for inheritance. A set of resources lead pupils through the history of this discovery. They explain how chromosomes recombine and which parts are more susceptible to this linkage....
Interactive
Cold Spring Harbor Laboratory

Chromosomes Carry Genes

For Students 9th - 12th Standards
Some traits only exist in males and some only in females. Pupils learn how the location of genes on sex chromosomes determines them using an interactive lesson. An animation illustrates how scientists know this to be true and shows how...
Interactive
Cold Spring Harbor Laboratory

Evolution Begins with the Inheritance of Gene Variations

For Students 9th - 12th Standards
Connect Mendelian genetics with Darwinian theories. An interactive lesson lets pupils explore how George Shull used research from other scientists to explore genetic variation. The resource outlines the statistical analysis of genetic...
Interactive
Cold Spring Harbor Laboratory

Specialized Chromosomes Determine Gender

For Students 9th - 12th Standards
Are you an XX or an XY? Budding scientists learn about cellular fertilization and the determination of gender in a thorough online lesson. They follow their study with a set of interactive reflection questions.
Interactive
Cold Spring Harbor Laboratory

Sex Cells Have One Set of Chromosomes; Body Cells Have Two

For Students 9th - 12th Standards
What's the difference between body cells and sex cells? Learners explore the question and the process of meiosis using an interactive lesson. An animation describes the discovery of meiosis and describes its phases for a detailed and...
Interactive
Cold Spring Harbor Laboratory

Genes Are Real Things

For Students 9th - 12th Standards
Proving microscopic structures exist is a difficult task. Learn how scientists did just that in the mid-1800s as they set out to identify the cellular structures related to genetics. The online lesson explains the collection of work that...
Interactive
Cold Spring Harbor Laboratory

Genetic Inheritance Follows Rules

For Students 9th - 12th Standards
Rules are not meant to be broken in genetics. Scholars learn to build Punnett squares to track the inheritance of dominant and recessive traits in an interactive animation activity. Online questions help individuals reflect on their...
Interactive
Cold Spring Harbor Laboratory

Some Genes Are Dominant

For Students 9th - 12th Standards
Dominate a lesson on genetic traits. Young scholars learn about the difference between dominant and recessive traits with an interactive lesson. An animation demonstrates Mendel's work on the inheritance of traits, and interactive...
Interactive
Cold Spring Harbor Laboratory

Genes Don't Blend

For Students 9th - 12th Standards
Yellow and blue make green—unless you're studying the inheritance of genetic traits. An interactive lesson explains the difference between blended traits and pure traits and gives examples of their occurrence. The resource includes a...
Interactive
Cold Spring Harbor Laboratory

Genes Come in Pairs

For Students 9th - 12th Standards
Mendel was the first to look at individual traits within a species. Step in his shoes as an interactive lesson takes users through his journey. An animation describes the design of his experiments and how he isolated individual traits to...
Interactive
Cold Spring Harbor Laboratory

Children Resemble Their Parents

For Students 9th - 12th Standards
Gregor Mendel's work revolutionized agriculture from an art to a science. Explore Mendel's work with an interactive lesson that includes animations, video, and practice problems. The instruction describes the early discoveries that...
Unit Plan
Princeton University

A Teacher's Guide to the Universe

For Teachers 9th - 12th Standards
Astronomers only observe four percent of the universe as the rest hides in darkness. The size, shape, and movement of the universe are the focus for an long-term high school unit. Its 43 lessons include hands-on experiments, direct...
Activity
Howard Hughes Medical Institute

The Mosquito Life Cycle Activity

For Teachers 9th - 12th Standards
Understanding the life cycle of a mosquito helps us understand how to prevent the spread of diseases they carry. A lab investigation provides learners with the opportunity to track the two-week life cycle of the mosquito. Scholars make...
Activity
Howard Hughes Medical Institute

Battling Vector-Borne Diseases: Factors That Affect the Mosquito Life Cycle

For Teachers 9th - 12th Standards
Slow the spread of disease by slowing disease carriers in their tracks. Learners explore just how they might accomplish this as they experiment with the life cycle of a mosquito under different conditions. Scholars design and conduct...
Activity
Howard Hughes Medical Institute

Beaks as Tools: Selective Advantage in Changing Environments

For Students 9th - Higher Ed Standards
How does nature select some adaptations over others? Scholars experiment picking up seeds with two different types of tools simulating beaks. After practicing, they experience a drought where one type of seed suddenly isn't available....
Activity
Howard Hughes Medical Institute

Evolution in Action: Data Analysis

For Teachers 9th - 12th Standards
An environmental factor, such as a drought, sometimes speeds up the rate of natural selection. Scholars analyze data on the beaks of birds around the time of the drought. They compare those that survived to those that perished and find...
Activity
Howard Hughes Medical Institute

Got Lactase? Blood Glucose Data Analysis

For Teachers 9th - 12th Standards
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...
Activity
Howard Hughes Medical Institute

Finding the Crater

For Teachers 7th - 12th Standards
A mass extinction event caused by an impact usually leaves a crater. Scholars use data from 10 different sites around the world trying to determine where to look for the crater. They use data, listing the amount of various minerals to...