Lesson Plan
Curated OER

Paper Chromatography

For Teachers 9th - 12th
Small groups of learners perform paper chromatography to separate food dyes into their component colors. Students perform the experiment and collect, organize, and represent their data to form an explanation of their outcomes. Learners...
Lesson Plan
Curated OER

Chromatography

For Teachers 6th - 12th
Students investigate the separation of mixtures using plant pigments. Using everyday items, they demonstrate the separation of pigments in plants through the process of chromatography.
Lesson Plan
Curated OER

Colored Dots 1

For Teachers 3rd - 8th
Students observe that colored markers are a mixture of many different colors by performing a chromatography experiment. They make observations, record information, and make generalized inferences from their observations.
Lesson Plan
Curated OER

Using Chromatography to Identify Unknowns

For Teachers 9th - 12th
Students are introduced to the concept of chromatography. They practice using new vocabular and observing experiments. They answer discussion questions to end the lesson.
Lesson Plan
Curated OER

Chromatography

For Teachers 7th - 10th
Students research types of chromatography and complete chromatography experiments.
Lesson Plan
Curated OER

The Conceptual Theory of Chromatography

For Teachers 9th - 12th
Students conduct a lab to determine the best way to separate a variety of mixtures choosing between paper, thin layer and column chromatography. They use chromatography techniques to identify unknown substances and submit a lab report on...
Lesson Plan
Curated OER

Hidden Colors

For Teachers K - 5th
Students discover presence of different colors hidden in green leaves by performing a chromatography experiment on chopped green leaves.
Lesson Plan
Curated OER

T-shirt Chromatography

For Teachers 5th - 8th
Students explore chromatography, a process used to separate mixtures. They create a colorful T-shirt design.
Lesson Plan
Curated OER

The Perils of Drinking Water

For Teachers 11th - 12th
Students determine the presence of drugs in water. In this chemistry instructional activity, students experiment on water samples using thin layer and column chromatography. They determine the concentration of drugs present using...
Lesson Plan
Curated OER

Chromatography

For Teachers 8th
Eighth graders observe a compound and separate it  into its component parts. In this chromatography lesson students complete and activity that demonstrates how mixtures can be separated into components. 
Lesson Plan
Curated OER

Thin-layer chromatography

For Teachers 10th - 12th
Students produce chromatograms of various vegetable extracts and standards. Using a flat bed scanner, they create a database of the results.
Lesson Plan
Curated OER

Using Ion Exchange Chromatography to Separate Proteins

For Teachers 9th - Higher Ed
Students explore protein purification by separating a positively charged molecule, lysozyme, from a negatively charged molecule, albumin, at neutral pH using ion exchange chromatography.
Lesson Plan
Curated OER

Mixing Colors

For Teachers 5th
Fifth graders perform experiments with color mixing and color changing. They observe the differences between physical and chemical changes and record their observations in journals.
Lesson Plan
Curated OER

Wolf Pack in a Bottle

For Teachers 9th - 12th
Students participate in an activity of a mock electrophoresis using paper chromatography to study DNA and genetic restriction mapping.
Lesson Plan
Curated OER

Science NetLinks: Color Burst

For Teachers 3rd - 5th
Students gain experience in asking questions and conducting inquiry by exploring the separation of colors in water and other solvents; to communicate and share findings of student investigations.
Lesson Plan
Curated OER

DNA Fingerprinting

For Teachers 6th - 8th
Middle schoolers experiment with chromatography as a technique which is similar to electrophoresis that scientists use to identify DNA samples.
Lesson Plan
Curated OER

Separation of Unknowns in a Liquid

For Teachers 4th - 5th
Students identify chromatography as method of separating the components of a liquid. Students discover that dyes are composed of more than one component in achieving a particular color in these lessons on paper chromatography.
Lesson Plan
Curated OER

Paper Chromatography

For Teachers 8th - 12th
Students participate in an experiment determining how to separate a mixture of dyes in water-soluble ink.
Lesson Plan
Curated OER

Introduction to Gas Chromatography

For Teachers 8th - 12th
Students analyze gas chromatograms and suggest various applications for gas chromatography.
Interactive
Carnegie Mellon University

Chem Collective: Qualitative and Quantitative Analysis of Food Dyes

For Students 9th - 10th
An interactive tutorial to determine the amount of dyes present in a powdered beverage in order to examine the allegation that the manufacturer is exceeding the allowable amount of the artificial food dyes in the drinks it produces.he...
Activity
Science Buddies

Science Buddies: Paper Chromatography: Advanced Version 1

For Students 6th - 8th
This project will teach you the basics of analytical chemistry, which is a must for students who want to go into chemistry or materials science. The molecules in objects we see all around us are constantly attracting each other....
Activity
Science Buddies

Science Buddies: Paper Chromatography: Advanced Version 2

For Students 6th - 8th
Chromatography is a method used to separate mixtures of compounds and to identify each compound in the mixture. You may have separated the different inks in a black marker by using a strip of paper and water. There are many different...
Activity
Science Buddies

Science Buddies: Make Your Own Markers

For Students 3rd - 5th
Do you ever wonder how markers are made? Where do all of those colors come from? Many of the colorful dyes we use come from plant pigments. Pigments are what make the world around us so colorful. How do chemists turn those natural plant...
Lesson Plan
Science Education Resource Center at Carleton College

Serc: Chromatography: Who Wrote the Note?

For Teachers 3rd - 6th
Students investigate who stole the class pet by testing the chromatograph of different markers as a way to find the evidence that points to the perpetrator.