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Lesson Plan
Curated OER

Bioinformatics

For Teachers 9th - Higher Ed
Young scholars conduct a series of scientific investigation using bioinformatics. In this molecular biology lesson plan, students collect experimental data using different educational softwares. They calculate and analyze relationships...
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Lesson Plan
Curated OER

Molecular Architecture

For Teachers 9th - 12th
High schoolers cuminate their study of molecular structure and bonding with this activity.
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Lesson Plan
LABScI

Atomic Structure and the Periodic Table of Elements: The Secret Agent Lab

For Students 9th - 12th
Food always gets attention! Model atomic structure using fruit loops to represent the subatomic particles. After building models, scholars create ionic bonds using their models. Finally, they use these concepts to create a periodic table.
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Lesson Plan
Curated OER

Genetics and Molecular Biology

For Teachers 9th - 10th
Students create DNA models using colored construction papers. In this biology lesson, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
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Lesson Plan
Curated OER

Creating an Enzyme-Substrate Model

For Teachers 9th - 12th
Students explore the reaction rates of an enzyme-mediated reaction through experimentation. In small groups, they use everyday objects to demonstrate the effects of environmental variables on enzyme function. Students graph and...
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Lesson Plan
Curated OER

Proteomics

For Teachers 9th - Higher Ed
Students analyze data taken from proteomic experiments. For this biology lesson, students explain the importance of bioinformatics tools in the study of proteins. They evaluate scientific results using math and computer software.
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Lesson Plan
Curated OER

Everything You Ever Wanted To Know About Hot Wire Chemical Vapor Deposition, But Were Afraid To Ask

For Teachers 10th - 12th
To wrap up your year of general chemistry, have lab groups compete in a tot wire chemical vapor deposition (HWCVD) competition. With their foundation in chemical nomenclature, stoichiometry, and gas laws, each group completes several...
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Lesson Plan
Curated OER

Transcription, Translation, and the Genetics of Microbes

For Teachers 11th - 12th
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
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Lesson Plan
Cornell University

The Making of Macromolecules

For Students 7th - 12th
Compare and contrast macromolecules made from the same elements. Young scholars learn how the structure of a molecule has as much influence on a compound as the elements in the molecule. They experiment with molecular model kits to...
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Lesson Plan
Curated OER

Respiration Challenge

For Teachers 11th - Higher Ed
Learners use limited data and their prior knowledge to solve problems focused on various inhibitors of respiration in this lesson on cellular respiration in a molecular level. This lesson includes a student handout and a pre-activity...
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Lesson Plan
Serendip

From Gene to Protein - Transcription and Translation

For Teachers 9th - 12th Standards
Learners identify the different steps involved in DNA transcription. For this genetics lesson, pupils complete a worksheet and model the translation process with a paper chain activity. They watch a video on sickle cell anemia and...
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Lesson Plan
Curated OER

Diffusion Across a Selectively Permeable Membrane

For Teachers 9th - 10th
Students investigate how water passes through cell membranes. In this biology lesson, students differentiate osmosis and diffusion. They illustrate the movement of water in both processes.
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Lesson Plan
Curated OER

An Enzyme- Substrate Model

For Teachers 8th - Higher Ed
Young scholars explore reaction rates of an enzyme-mediated reaction. They examine the effects of environmental variables on enzyme function. Students collect, graph, and analyze data relating to the reaction.
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Lesson Plan
Curated OER

21st Century Medicine: Nerves of Steel

For Teachers 9th - 12th
Learners model a sarcomere's action, they gain a kinesthetic and visual understanding of muscle contraction. They use this exercise stimulates the production of myosin and actin. Students use two colors of clay, make a "sandwich" of...
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Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting

For Teachers 9th - 11th
Students explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
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Lesson Plan
Curated OER

The Challenge to Deliver Insulin

For Teachers 5th - 9th
Students study the types of diabetes and why insulin is important.  In this diabetes lesson students build molecular models and create a healthy lifestyle plan. 
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Lesson Plan
Curated OER

How Genes Work Lesson Plan

For Teachers 9th - 12th
High schoolers define the key terms that are the structure and function of DNA. In this genetics lesson plan students complete a lab activity in which they construct a model DNA structure.
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Lesson Plan
Curated OER

How Mutations Lead to Changes in Cell Structure and Function

For Teachers 9th - 12th
Students investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare...
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Lesson Plan
Curated OER

Pharmaceuticals and Treatments

For Teachers 12th - Higher Ed
Students perform an experiment involving reverse transcriptase-polymerized chain reaction HIV replication to better examine the biotechnology used by scientists in pharmaceutical research of infections diseases like HIV. Students examine...
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Lesson Plan
Curated OER

DNA Extraction from Yeast Cells

For Teachers 8th - 10th
Students explore DNA. They work in groups and mix prepared detergent/ salt solution, meat tenderizer solution, Fleischman's yeast and water to extract DNA from yeast. Observations are recorded.
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Lesson Plan
Serendip

From Gene to Protein via Transcription and Translation

For Teachers 9th - 12th Standards
DNA carries the codes for creating just the right protein. A well-designed lesson plan leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
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Lesson Plan
Curated OER

18th Century Microscope

For Teachers K - 12th
Students examine a microscope from the 18th century. In this microscope lesson, students investigate how it works, what it was used for and how the tool has evolved through the years. Students also build knowledge on how compound...
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Lesson Plan
Curated OER

Gene Regulation Mechanisms

For Teachers 11th - Higher Ed
Students explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
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Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis

For Teachers 10th - 12th
Young scholars create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...