Curated OER
Characterization of the Bioluminescence (Lux+) Gene E. coli
Students grow E. coli strain HB101, which contains the plasmid pUCD607 with the bioluminescence (Lux+) gene. The plasmid containing the Lux+ gene is isolated from the E. coli, then characterized by restriction analysis.
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Bioinformatics
Young scholars conduct a series of scientific investigation using bioinformatics. In this molecular biology lesson plan, students collect experimental data using different educational softwares. They calculate and analyze relationships...
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The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
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From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson plan leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
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Genetics and Molecular Biology
Students create DNA models using colored construction papers. In this biology lesson, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
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How Genes Work Lesson Plan
High schoolers define the key terms that are the structure and function of DNA. In this genetics lesson plan students complete a lab activity in which they construct a model DNA structure.
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Molecular Approaches to Evolution
High schoolers examine the molecular studies of organisms that have led to a new era in their understanding of speciation and evolutionary relationships. Students study the allelic frequency of genes controlling specific molecules and...
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From Gene to Protein - Transcription and Translation
Learners identify the different steps involved in DNA transcription. For this genetics lesson, pupils complete a worksheet and model the translation process with a paper chain activity. They watch a video on sickle cell anemia and...
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Molecular Approaches to Evolution
Students are introduced to working with molecular data. The first activity does both simulated and original data are used to compare amino acid, protein or DNA differences to construct phylogenetic trees or cladograms. These activities...
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Trichinella Forensics
Students engage in DNA manipulation using forensics techniques. Students investigate topics involved in forensics studies such as cloning, electrophoresis, gene mapping, replication, and transcription.
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Gene Regulation Mechanisms
Students explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
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Determination of Phylogenetic Relationships Using Restriction Analysis
Students applied various mathematical analyses to interpret their data. By using the resulting DNA fragment patterns from several enzymes students established a possible evolutionary relationship among the mice.
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Biotechnology
Students explore biotechnology through various activities. In this biology lesson, students analyze its pros and cons. They study and read informative articles about biotechnology.
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Bacterial Transformation Kit
Learners participate in an experiment in which they practice moving genes from one organism to another. They examine the results of a recombination of jellyfish. They identify different types of bacteria as well.
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Blood Business
Students identify the different kinds of blood. In this biology lesson, students investigate the antigens, agglutinins and Rh factor using their own blood. They use Punnett squares to predict blood type of offspring.
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Electrophoretic Analysis: DNA Fingerprinting and Evolutionary Divergence
Young scholars examine the principles of electrophoresis. They evaluate both the agarose and polyacrylamide system of molecular separation. In order to bring the concepts of genetics and evolution full circle from DNA to protein,...
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Transcription, Translation, and the Genetics of Microbes
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
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Electrophoretic Analysis: DNA Fingerprinting and Evolutionary Divergence
Students examine the principles of electrophoresis. They evaluate both the agarose and polyacrylamide system of molecular separation. In order to bring the concepts of genetics and evolution full circle from DNA to protein, students...
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Genetic Engineering
Students examine the advantages and disadvantages of genetic engineering. In this genetics activity students simulate the genetic engineering of a human insulin gene.
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UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
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The Cytochrome-C Lab
Students examine a method biologists use to try to determine relationships. They examine how amino acid sequences have been determined for a number of proteins, and how scientists can make inferences about DNA based on the amino acid...
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DNA Fingerprinting
Students study the process of DNA Fingerprinting and how DNA Fingerprinting is used in solving crimes. They examine a crime scenario that involves collecting DNA Fingerprinting information from blood collected at the crime scene. They...
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Proteins Expressed At Different Stages
Young scholars investigate protein electrophoresis in a lab setting. Full laboratory equipment is needed and safety should be taught. The level of prior knowledge needed to perform lab is high and is ideal for an honors class.
Curated OER
Alcohol Tolerance in Drosophila and You
Students develop and run a laboratory comparing alcohol tolerance in flies with and without the ADH enzyme.