Lesson Plan
Curated OER

Allele and Phenotype Frequencies in Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Interactive
Cold Spring Harbor Laboratory

Mutations Are Changes in Genetic Information

For Students 9th - 12th Standards
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Activity
Howard Hughes Medical Institute

Molecular Genetics of Color Mutations in Rock Pocket Mice

For Teachers 9th - 12th Standards
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Interactive
Cold Spring Harbor Laboratory

Some Types of Mutations Are Automatically Repaired

For Students 9th - 12th Standards
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Activity
Howard Hughes Medical Institute

The Molecular Evolution of Gene Birth and Death

For Teachers 9th - 12th Standards
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Activity
Howard Hughes Medical Institute

Natural Selection and Evolution of Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Activity
Howard Hughes Medical Institute

Color Variation Over Time in Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
While many mutations are neutral, those that appear advantageous increase in frequency in a population. Scholars use illustrations to make predictions about populations of mice. They follow it up with a video to confirm or refute their...
Interactive
Cold Spring Harbor Laboratory

Genes Can Be Moved Between Species

For Students 9th - 12th Standards
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Interactive
Cold Spring Harbor Laboratory

One Gene Makes One Protein

For Students 9th - 12th Standards
Very few universities still offer a master's degree in the ecology of grasses, but that was the degree that led George Wells Beadle to an interest in genetics and later a Nobel Prize. Scholars learn about the discoveries of Dr. Beadle...
Lesson Plan
Curated OER

Design Yer Genes

For Teachers 7th
Seventh graders explore general structure of and natural changes that occur in DNA strands, and discuss concept of genetic engineering by creating small portion of strawberry chromosome with three genes, modeling naturally occurring...
Lesson Plan
Curated OER

Gene Action and Mutation

For Teachers 10th - 12th
Students review terms related to DNA structure and function. They complete a variety of worksheets in small groups or in pairs reflecting the unit's concepts regarding DNA. They submit their worksheets for grading.
Lesson Plan
Curated OER

Blue Genes: Affect Your Life!

For Teachers 6th - 12th
Students, in groups, research, analyze and synthesize information on genetic diseases. After watching a video on genetics, groups perform research on a variety of genetic diseases and present their findings to the class.
Lesson Plan
Curated OER

DNA and Genetic Expression

For Teachers 10th - 12th
Students, in groups, complete a worksheet on DNA transcription and translation. They determine codons for particular amino acids. They attempt to introduce mutations to determine what will happen to the DNA sequence.
Lesson Plan
Curated OER

Punnett Squares/Genetics

For Teachers 9th
Ninth graders complete a monohybrid cross and a dihybrid cross. In this biology instructional activity, 9th graders predict the traits of offspring using the Punnett square. They differentiate recessive and dominant genes.
Interactive
Cold Spring Harbor Laboratory

Living Things Share Common Genes

For Students 9th - 12th Standards
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Interactive
Cold Spring Harbor Laboratory

DNA Is Only the Beginning for Understanding the Human Genome

For Students 9th - 12th Standards
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...

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