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Curated OER
Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Howard Hughes Medical Institute
Color Variation Over Time in Rock Pocket Mouse Populations
While many mutations are neutral, those that appear advantageous increase in frequency in a population. Scholars use illustrations to make predictions about populations of mice. They follow it up with a video to confirm or refute their...
Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Cold Spring Harbor Laboratory
One Gene Makes One Protein
Very few universities still offer a master's degree in the ecology of grasses, but that was the degree that led George Wells Beadle to an interest in genetics and later a Nobel Prize. Scholars learn about the discoveries of Dr. Beadle...
Curated OER
Design Yer Genes
Seventh graders explore general structure of and natural changes that occur in DNA strands, and discuss concept of genetic engineering by creating small portion of strawberry chromosome with three genes, modeling naturally occurring...
Curated OER
Gene Action and Mutation
Students review terms related to DNA structure and function. They complete a variety of worksheets in small groups or in pairs reflecting the unit's concepts regarding DNA. They submit their worksheets for grading.
Curated OER
Blue Genes: Affect Your Life!
Students, in groups, research, analyze and synthesize information on genetic diseases. After watching a video on genetics, groups perform research on a variety of genetic diseases and present their findings to the class.
Curated OER
DNA and Genetic Expression
Students, in groups, complete a worksheet on DNA transcription and translation. They determine codons for particular amino acids. They attempt to introduce mutations to determine what will happen to the DNA sequence.
Curated OER
Punnett Squares/Genetics
Ninth graders complete a monohybrid cross and a dihybrid cross. In this biology instructional activity, 9th graders predict the traits of offspring using the Punnett square. They differentiate recessive and dominant genes.
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
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