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Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Curated OER
The Watson-Crick Model of DNA Structure
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Curated OER
DNA Sequencing Simulation
Young scholars explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Curated OER
Forensic Files: A DNA Dilemma
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Science 4 Inquiry
The Monster Mash
Young scientists create monsters by applying their knowledge of transcription and translation. They randomly find the DNA, assign it a codon, and build monsters piece by piece.
Curated OER
The Structure of DNA
Students describe the structure of the double helix, explain how DNA copies itself, and recognize that the sequence of DNA is what makes each individual unique.
Curated OER
Where's the CAT? a DNA Profiling Simulation.
Young scholars explore DNA technology. Students participate in a simulation to perform at the basic steps of a DNA profile. They observe copies of DNA sequences, construct DNA probes, and discuss outcomes of their experiment.
Curated OER
Using Amino Acid Sequences to Show Evolutionary Relationships
Compare protein fragments, count amino acids, and use the information to explore common ancestry. The resource mentions a student worksheet, however, a separate printable worksheet is not provided. The exercises are written into the...
Curated OER
DNA Chips
Students discover what they need to know about DNA chips. They extend this knowledge to analyze gene expression data to diagnose two kinds of leukemia.
Curated OER
My Science Box: DNA Fingerprinting
Pupils identify DNA in a crime scenario. In this DNA lesson, students perform paper chromatography and compare it against the pens of various suspects.
Curated OER
DNA Sequencing Model Lab
Students pretend they are each genetic engineers with a test tube of unknown DNA (PCR'd) possibly taken from blood cells of someone with a genetic condition.
Curated OER
Polymerase Chain Reaction (PCR)
Students explore how PCR works through various activities. In this biology lesson, students explain how PCR generate copies of DNA. They simulate the process using an online interactive website.
Curated OER
Gel Electrophoresis
Students conduct a variety of experiments to explore gel electrophoresis. In this biology instructional activity, explain how this process separate DNA and RNA. They discuss the practical applications of this method.
Curated OER
Protein Synthesis Activities
Students participate in a teacher-guided activity to teach about protein synthesis. Student roles include one person as the DNA molecule, another is a single stranded sequence of complementary mRNA.
Curated OER
DNA Fingerprinting
Ninth graders investigate what restriction enzymes do, and explain how a DNA sample can link a suspect to a crime.
Curated OER
Electrophoresis Analogy
Students participate in a simulation of electrophoresis separation of DNA fragments. They link arms to form DNA fragments with each student representing a nucleotide. As they move through an obstacle course they discover how fragments...
Curated OER
Recovering the Romanovs
Students use DNA to solve an identity mystery. In this biology lesson, students use the Internet to gather information about sex-linked disorders and complete a Punnett square for hemophilia, then examine a handwriting analysis, ear...
Curated OER
Ghost in Your Genes
Learners explore DNA microarrays. In this genetics lesson, students model DNA microarrays that are used by scientists. Learners work to determine levels of breast cancer genes in patients. They will determine the treatment required based...
Curated OER
Pliable Proteins
Students make models of protiens using wire and paperclips. They are given step by step instructions with lots of information about proteins throughout the directions. They make the three basic structual elements of proteins;...
Concord Consortium
Modeling Translation
An mRNA sequences make proteins, the most common molecules in cells. Young scientists observe translation of mRNA on ribosomes. They view them forming amino acids. Finally, the amino acids curl into proteins.
Curated OER
Visualizing a Human Gene with Its Introns & Exons
Students examine the entire DNA base sequence of the human adenosine deaminase gene after it is printed out from the source disk provided. The enormous length of a single gene as well as the immense difference in length between intron...