Cold Spring Harbor Laboratory
A Gene Is a Discrete Sequence of DNA Nucleotides
Frederick Sanger won two Nobel prizes for protein sequencing and DNA sequencing. Young scientists learn about Dr. Sanger's research and amazing discoveries. They read an article and a biography, view videos and animations, and apply...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Cold Spring Harbor Laboratory
Some DNA Does Not Encode Protein
Roy John Britten easily earned a PhD in nuclear physics—but he found painting with water colors too difficult. Young scientists learn about Britten's life, career, and research with an online interactive. They read a biography, view...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Cold Spring Harbor Laboratory
DNA Responds to Signals from Outside the Cell
How do cells know when to replicate, transcribe, and stop? James E. Darnell, Jr. shifted from studying medicine to biochemistry and decided to address this mystery. Learn about his research, discoveries, and the impact on future medical...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Field Museum
The Case of Darwin's Finches
One of the most striking pieces of evidence for Darwin's Evolution of Species was his observations of finches and how their beaks differed from island to island, depending on their primary food sources. So what would happen to the theory...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...