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How Mutations Lead to Changes in Cell Structure and Function
Students investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare...
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Genetic Jewels: Building the DNA Model
Students construct segments of DNA to create a piece of jewelry. In this genetics lesson students create a DNA sequence that they turn into something to wear.
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Pseudogene Suite
Learners use Biology Workbench to explore DNA sequence data for the GULOP gene in humans, chimpanzees, orangutans, and crab-eating macaques and the beta globin gene and its pseduogene in humans, gorillas, and chimpanzees.
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Protein Factory
Learners examine protein synthesis and how DNA is transcribed. In this investigative instructional activity students play a role in the messenger RNA when it creates nucleotides.
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Protein Synthesis
In this science related worksheet, students study, locate and answer ten multiple choice questions dealing with protein synthesis.
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Scientist Simulation
Students envision the work of a research scientist, and the relationship between molecular biology and medicine. This activity allows students to imagine themselves working as research scientists by asking them to complete the end-steps...
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Protein Factory
Students discuss the steps of protein synthesis before acting out the process as a class. They are assigned specific roles and receive an instruction card and get materials listed in order to perform their role. Students switch roles...
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Investigating Evolutionary Questions: Bats, Whales, Reptiles, Birds, Animal Classification
Students are guided through a process in which three questions are addressed by retrieving beta hemoglobin sequences from online databases, and using online tools to compare those sequences in student-selected animals.
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Evolutionary Relationships Based Upon Comparative Genetics
Students investigate the protein cytochrome c in an attempt to use its genetic chemistry to study possible evolutionary relationships between organisms. The lesson integrates technology with the use computers to perform DNA analysis.
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Molecular Approaches to Evolution
Students are introduced to working with molecular data. The first activity does both simulated and original data are used to compare amino acid, protein or DNA differences to construct phylogenetic trees or cladograms. These activities...
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Translating Genetic Information
Students explore the process of translation. They determine the correct sequencing and present their strands to the class. In addition, they compare normal red blood cells to sickle cells and complete discussion questions.
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Who Stole My Salad?
Eighth graders explain how protein is made in the cell. In this biology activity, 8th graders translate RNA and DNA using an internet database. They determine the thief based on evidence collected.
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DNA Code
Students synthesize information gathered from the web on reading the DNA code. In this upper-level biology lesson plan, students use an online resource to gain information about DNA codes and then create posters on what they have...
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Genetics
In this activity, students will answer 4 fill in the blank statements about Mendelian inheritance and meiosis. Then students will use Punnett squares to answer three short answer questions. Students will match 8 genetics vocabulary words...
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Protein Synthesis
In this biology worksheet, students complete a crossword puzzle with 35 questions on protein synthesis. They identify the different parts of the cell involved in the process.
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BLAST Algorithm
Students explore a series of activities on using BLAST. In this biology lesson, students explain the significance of BLAST in DNA query. They give real world applications of BLAST.
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Scientist Simulation
High schoolers imagine themselves working as research scientists completing the end-steps of a molecular research project and interpreting the data. They compare the gene sequences of normal and abnormal mice and evaluate the protein...
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Why Do We Need Vitamin C in Our Diet?
Students compare/contrast the DNA sequence data of the rat GULO gene to the inactive human GULO gene. They translate and align the sequences, and propose a scenario to explain the occurrence of an inactive DNA sequence to that of an...
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Why do we need Vitamin C in our diet? Or Why do we carry old inactive genes in our genome?
Students explore and explain how mutations in the DNA sequence of a gene may be silent or result in phenotypic change in an organism and in its offspring. They analyze how evolution and biodiversity are the result of genetic changes that...
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Candy DNA Model Lesson
Students explore DNA structure using materials such as Twizzlers, small colored gumdrops and/or toothpicks.
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DNA Vocabulary Review
In this DNA worksheet, students review vocabulary words associated with DNA, DNA replication, and gene expression. This worksheet has 13 matching questions.
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Biology Honors Final Project
Tenth graders work on a project about cellular biology and genetics. In this biology instructional activity, 10th graders research about the assigned human body system and genetic disorders that affect it. They create a multimedia...
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Temperature and the Tomato
You will need a photovoltaic system and monitor at your school in order to obtain all of the data required to thoroughly implement this lesson. Your class monitors daily temperature and insolation amounts over a two week span of time....
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Control of Eukaryotic Genes
Covering the molecular interactions involved with DNA packing and the control of gene activity in depth, this slideshow is useful for higher-level biology students. The biochemical components of protein translation are diagrammed and...