Curated OER
The Conceptual Theory of Chromatography
Students conduct a lab to determine the best way to separate a variety of mixtures choosing between paper, thin layer and column chromatography. They use chromatography techniques to identify unknown substances and submit a lab report on...
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Chromatography
Students research types of chromatography and complete chromatography experiments.
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Programming the "Rinse Robot"
Experienced chemistry technicians use then layer chromatography to discover how much of a free compound is left after each rinse cycle. Where this could obviously be used as a practice with chromatography technique, it can also be used...
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Major Organic Acids in Fruits
Young scholars investigate the organic acids present in a variety of juices. In this organic acids lesson plan, students read about the effects of organic acids in juices. They use paper chromatography to separate out the acids present...
Kenan Fellows
An Analytical Chemist, a Biochemist, an Animal Scientist, and an Oncologist Walk into a Lab...No Joke
Oncology presents multiple opportunities for research and the collaboration of many different types of scientists. Scholars divide into groups and research the history of mass spectrometry, polarity/non-polarity,...
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Introducing Chromatography
Students investigate chromatography. In this chromatography lesson plan, students investigate a lab set up for chromatography.
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Straw Chromatography
Learners separate food coloring using liquid chromatography. In this chemistry lesson, students explain the effects of different solvents on the rate of separation.
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Investigating Plant Pigments: A Guided Inquiry Laboratory Experiment
Students participate in a three-part lab in which they investigate plant pigments. Part I is designed to teach basic laboratory techniques of column chromatography, in Part II students design an experiment to separate the components of a...
Curated OER
BioFuels: The Chemistry and Economics of Alternative Fuels
Junior chemists manufacture biodiesel in the lab. In this exercise, they check the purity of the biodiesel using thin layer chromatography. They also calculate its density and heat of combustion. They are sure to rise to the challenge...
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Coloring Fabrics With Dyes from Plant Materials K-12 Experiments & Background Information
Students investigate the effects of acid and bases on dyes made with plant materials. In this chromatography lesson students predict color outcomes and complete a lab activity on color combinations.
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Activities for a High School Instrumentation Course
The intent of this series of activities is to introduce high schoolers to the field of chemical instrumentaiton. They perform a few basic chemistry lab techniques: pH titration, paper, gas, and liquid chromatography, ultraviolet and...
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Introduction to Gas Chromatography
Students analyze gas chromatograms and suggest various applications for gas chromatography.
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Drug Analysis Using Thin-Layer Chromatography
Students use forensic science to positively identify any suspected drugs submitted to the laboratory. They determine the identity of the drugs found in the bodies of drug-overdose victims. Students use TLC to identify the active...
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Who Done It?
Pick and choose which activities to include in this crime scene investigation. Junior detectives can examine fingerprints, DNA, blood samples, or bone structure. The plan suggests you have teams solve a mystery, but it does not give you...
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Chromatographic Separation of Methylene Blue and Sodium Fluorescein
Students determine the best solvent system for separating a methylene blue/sodium fluorescein mixture by thin layer chromatography. They conduct an initial TLC separation using ethanol and a different solvent mixture and analyze the data...
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Leaf Chromatography
You can bring science alive for students with these lessons on leaf pigments.
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Cell Structures and Their Functions
Life science learners investigate live cells. They examine wet mount slides of cyanobacteria and Elodea plants. They peer into the dynamic microscopic world of protists. Afterward, they construct a model of a cell, including rudimentary...
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Paper Chromatography
Students participate in an experiment determining how to separate a mixture of dyes in water-soluble ink.
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Molecular Evolution in Plants
High schoolers are using a paper chromatography study that is suitable for introductory biology. The absorption spectra studies and gel electrophoresis studies are appropriate for students who have complete both introductory biology and...
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Separation of Unknowns in a Liquid
Learners identify chromatography as method of separating the components of a liquid. Students discover that dyes are composed of more than one component in achieving a particular color in these lessons on paper chromatography.
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Wolf Pack in a Bottle
Students participate in an activity of a mock electrophoresis using paper chromatography to study DNA and genetic restriction mapping.
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The Perils of Drinking Water
Young scholars determine the presence of drugs in water. In this chemistry lesson, students experiment on water samples using thin layer and column chromatography. They determine the concentration of drugs present using graphical analysis.
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DNA Fingerprinting
Pupils experiment with chromatography as a technique which is similar to electrophoresis that scientists use to identify DNA samples.
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