Lesson Plan
Virginia Department of Education

Genetic Variation and Mutations

For Teachers 9th - 12th
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book,...
PPT
Biology Junction

Cellular Division

For Students 9th - 12th Standards
Based on current scientific knowledge, all cells come from preexisting cells. Scholars learn about cell division, cell replication, mitosis, meiosis, and more with a PowerPoint. It describes the differences between prokaryotes and...
Lesson Plan
Curated OER

Reaching Into Your Genes

For Teachers 6th - 12th
Students interact with a video to explore the basis for the science of chromosomes. They perform a chromosomal analysis called a karyotype and explore how seemingly minute errors in chromosomes can lead to devastating illnesses.
Lesson Plan
Curated OER

Genetics 4 Mutations

For Teachers 7th - 11th
Students identify and illustrate how changes in DNA cause mutations and evaluate the significance of these changes. They illustrate a chromosomal mutation such as duplication, deletion, inversion, and translocation.
Lesson Plan
Curated OER

Don't Delete Me

For Teachers 4th
Fourth graders explore genetic disorders, which can be caused by a malfunction in a particular chromosome and how these can cause genetic mutation.
Lesson Plan
Curated OER

Mutations and Cancer

For Teachers 9th - 12th
Students study how cancer cells mutate and affect cell division.  In this investigative lesson students view a PowerPoint presentation learn the seven warning signs of cancer. 
Lesson Plan
Curated OER

Genetic Disorders

For Teachers 8th - 12th
Students examine how living cells create new cells and how genetic mutations can cause disorders and be inherited.  In this genetic reproductionn lesson students create their own PowerPoint presentation. 
Lesson Plan
Curated OER

Modeling Allele Distribution Through Meiosis and Fertilization

For Teachers 9th - 12th
The main objective of this activity is to illustrate the variation that results from crossing-over during prophase I of meiosis. Other sources of variation from generation to generation are: (1) independent assortment (223 possible...
Lesson Plan
Curated OER

Who's the Father?

For Teachers 11th - Higher Ed
Pupils analyze gels to determine parentage in this lesson about scientific evidence, investigation, and DNA concepts. The lesson includes a pre-activity worksheet, a final individual assessment, and student handouts for in-class...
Article
Genome British Columbia

Genome British Columbia: Chromosome Fundamentals

For Students 9th - 10th
Understanding how chromosomes, DNA and genes all work together can be confusing. The author has explained how chromosomes fit into the picture in clear language.
PPT
Other

Genome British Columbia: Chromosomes

For Students 9th - 10th
This is an excellent PowerPoint presentation that explains what chromosomes are. Many slides are also accompanied by detailed notes.
Graphic
National Health Museum

Access Excellence: Human Chromosomes

For Students 9th - 10th
This map from Access Excellence shows human chromosome pairs. The site includes a short description of chromosome structure, staining of chromosomes and karyotypes.
Interactive
Cold Spring Harbor Laboratory

Dolan Dna Learning Center: Dna Molecule: Chromosome Map

For Students 9th - 10th
Find out about the chromosome karyotype and how that identifies a human as a human. [0:46]
Activity
University of Arizona

Biology Project: Karyotyping Activity

For Students 9th - 10th
If you want an interactive way to practice karyotyping, this is it. There are three patient histories and karyotypes to use in diagnosing human genetic disorders. There is enough information on comparing chromosomes to get you started.
Interactive
University of Utah

University of Utah: Genetics Learning Center: learn.genetics: Make a Karyotype

For Students 9th - 10th
Drag and match the chromosome pairs to organize this human karyotype profile.
Handout
CK-12 Foundation

Ck 12: Biology: Human Chromosomes and Genes Study Guide

For Students 9th - 10th
This comprehensive study guide covers the main terms and concepts needed for a unit on human chromosomes and genes.
Interactive
University of Arizona

Biology Project: Karyotyping Activity

For Students 9th - 10th
Try your hand at matching chromosomes to complete the karyotype in this simulation. Simulation contains karyotyping activity for three different patients and students can explore whether those patients have any genetic disorders.
Interactive
University of Utah

University of Utah: Learning Center: Learn Genetics: Using Karyotypes to Predict

For Students 9th - 10th
Follow a series of chromosome problem scenarios to learn about several genetic disorders. Test your knowledge with a quiz at the end of the exercise.
Handout
Palomar Community College District

Human Chromosomal Abnormalities (Tutorial)

For Students 9th - 10th
A self paced tutorial covering chromosomal testing and the many types of conditions resulting from chromosome abnormalities.
Lesson Plan
Indiana University

Ensi: Comparison of Human: Chimpanzee Chromosomes Lesson

For Teachers 9th - 10th
This is a great lesson plan that combines Karoytypes and evolution. Students will recognize that the chromosomes of chimpanzees and humans are remarkably similar, then correlate that to their evolutionary relationship.
Handout
University of Arizona

The Biology Project: Human Biology: New Methods for Karyotyping

For Students 9th - 10th
Read about the findings from the scientific group from the National Center for Human Genome Research, which published a modification to traditional karyotyping that permits rapid identification of chromosomal alterations.
Interactive
Other

Science.ca: Uchida Chromosome Mapping Game

For Students 9th - 10th
This game has students matching pairs of chromosomes to determine if there are any extras, indicating Down Syndrome.
Graphic
University of Washington

Uwmc Cytogenetics Laboratory: Cytogenetics Gallery

For Students 9th - 10th
This site opens with an excellent introduction to Cytogenetics. Explore this site to learn about chromosomes, human karyotypes and more.
Interactive
Palomar Community College District

Flashcards for Human Chromosomal Abnormalities

For Students 9th - 10th
Great for a quick check of facts related to detection and common abnormalities. Use these for a test review.

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