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Curated OER
The Watson-Crick Model of DNA Structure
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Curated OER
DNA Detectives
In order to understand DNA fingerprinting, advanced biology aces divise a crime scenario and analyze three different samples of lambda DNA. This creative lesson plan provides practice with micropipettes, electrophoresis boxes, and other...
Curated OER
Innocent or Guilty: A Lab on DNA Gel Electrophoresis
Students use the prelab as an introduction to the importance of DNA fingerprinting- a form of identification that us being accepted by both scientific and leagl experts. They prepare a gel for electrophoresis. DNA fragments, which have...
Virginia Department of Education
Building a DNA Model
It has been decades since the discovery of DNA. Still, activities such building this DNA model allow blossoming scientists to better understand the components that form this overall structure. During this activity, they will also...
Virginia Department of Education
DNA Structure, Nucleic Acids, and Proteins
What is in that double helix? Explain intricate concepts with a variety of creative activities in a activity that incorporates multiple steps to cover DNA structure, nucleic acids, and proteins. Pupils explore the history of DNA...
Beyond Benign
Gelin’: Gel Electrophoresis Simulation
Take a look at a DNA fingerprint. Scholars run a gel electrophoresis simulation to examine the DNA of potential father cats in the eighth installment of an 18-part series. The lesson continues the series that explores DNA and its...
California Academy of Science
Color Vision Genetics Evolution Simulation
At one point, all mammals carried only two color receptors, but now most humans carry three. An informative presentation and hands-on activity demonstrate how this evolved through genetics. By participating in the activity, pupils...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Forensic Files: A DNA Dilemma
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Curated OER
DNA Replication
Students create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Curated OER
The Great Cafeteria Caper
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Curated OER
DNA Sequencing Simulation
Students explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
Curated OER
Constructing a Phylogenetic Tree Using DNA Sequence Data
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Curated OER
DNA Fingerprinting
Young scholars discuss DNA Fingerprinting and gel electrophoresis before participating in a crime solving activity. Students simulate their DNA using adding tape and complete the steps necessary to do a gel electrophoresis. They...
Curated OER
Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
Curated OER
The Coding of Protein Molecules by DNA
Students investigate the production of proteins by the DNA. In this protein synthesis lesson plan, students use paper models to explore transcription and translation to make proteins using DNA. Students answer 10 questions to demonstrate...
Curated OER
lambda DNA Fingerprinting Simulation
Students perform restriction digests on DNA samples from four individuals, and then search for similarities between the individuals by running the restriction fragments on an electrophoresis gel.
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Curated OER
DNA Sequencing Simulation
High schoolers simulate the Sanger method of DNA sequencing using color pop-beads as a representation of nucleotides and dideoxynucleotides. Students assemble DNA sequences and run their sequences through a "sequencing gel" and sketch...
Curated OER
Where's the CAT? a DNA Profiling Simulation.
Students explore DNA technology. Students participate in a simulation to perform at the basic steps of a DNA profile. They observe copies of DNA sequences, construct DNA probes, and discuss outcomes of their experiment.
Curated OER
Simulation of Gene Splicing
Pupils simulate gene splicing by examining bacteria. They create a bacterial DNA into which they insert the human DNA (gene) that codes for growth hormone. They cut the sites of the enzyme to study how the human DNA can be joined to...
Curated OER
DNA Fingerprinting: You Be the Judge!
Young scholars use their knowledge of DNA fingerprinting to evaluate the use fingerprints in courts, and will address the ethics of establishing a national database of fingerprints.
Curated OER
DNA Fingerprinting: You Be the Judge!
Students explore DNA fingerprinting. Students discover how DNA fingerprinting is done and judge the validity. They evaluate the use of certain prints in courts and address the ethics of establishing a national database of fingerprpints.