Lesson Plan
Curated OER

The Watson-Crick Model of DNA Structure

For Teachers 7th - 10th
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Lesson Plan
Curated OER

DNA Detectives

For Teachers 10th - 12th
In order to understand DNA fingerprinting, advanced biology aces divise a crime scenario and analyze three different samples of lambda DNA. This creative lesson plan provides practice with micropipettes, electrophoresis boxes, and other...
Lesson Plan
Curated OER

Innocent or Guilty: A Lab on DNA Gel Electrophoresis

For Teachers 8th - 12th
Students use the prelab as an introduction to the importance of DNA fingerprinting- a form of identification that us being accepted by both scientific and leagl experts. They prepare a gel for electrophoresis. DNA fragments, which have...
Lesson Plan
Virginia Department of Education

Building a DNA Model

For Teachers 9th - 12th
It has been decades since the discovery of DNA. Still, activities such building this DNA model allow blossoming scientists to better understand the components that form this overall structure. During this activity, they will also...
Lesson Plan
Virginia Department of Education

DNA Structure, Nucleic Acids, and Proteins

For Teachers 9th - 12th
What is in that double helix? Explain intricate concepts with a variety of creative activities in a activity that incorporates multiple steps to cover DNA structure, nucleic acids, and proteins. Pupils explore the history of DNA...
Lesson Plan
Beyond Benign

Gelin’: Gel Electrophoresis Simulation

For Teachers 6th - 8th
Take a look at a DNA fingerprint. Scholars run a gel electrophoresis simulation to examine the DNA of potential father cats in the eighth installment of an 18-part series. The lesson continues the series that explores DNA and its...
Lesson Plan
California Academy of Science

Color Vision Genetics Evolution Simulation

For Teachers 7th - 12th Standards
At one point, all mammals carried only two color receptors, but now most humans carry three. An informative presentation and hands-on activity demonstrate how this evolved through genetics. By participating in the activity, pupils...
Lesson Plan
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Howard Hughes Medical Institute

Got Lactase? The Co-Evolution of Genes and Culture

For Teachers 8th - 12th Standards
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Lesson Plan
Curated OER

Forensic Files: A DNA Dilemma

For Teachers 7th - 12th
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Lesson Plan
Curated OER

DNA Replication

For Teachers 9th - 10th
Students create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Lesson Plan
Curated OER

The Great Cafeteria Caper

For Teachers 11th - Higher Ed
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Lesson Plan
Curated OER

DNA Sequencing Simulation

For Teachers 9th - 11th
Students explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
Lesson Plan
Curated OER

Constructing a Phylogenetic Tree Using DNA Sequence Data

For Teachers Higher Ed
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Lesson Plan
Curated OER

DNA Fingerprinting

For Teachers 7th - 8th
Young scholars discuss DNA Fingerprinting and gel electrophoresis before participating in a crime solving activity. Students simulate their DNA using adding tape and complete the steps necessary to do a gel electrophoresis. They...
Lesson Plan
Curated OER

Sequencing the Cystic Fibrosis Gene: A Simulation

For Teachers 9th
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
Lesson Plan
Curated OER

The Coding of Protein Molecules by DNA

For Teachers 9th - 12th
Students investigate the production of proteins by the DNA. In this protein synthesis lesson plan, students use paper models to explore transcription and translation to make proteins using DNA. Students answer 10 questions to demonstrate...
Lesson Plan
Curated OER

lambda DNA Fingerprinting Simulation

For Teachers 11th - 12th
Students perform restriction digests on DNA samples from four individuals, and then search for similarities between the individuals by running the restriction fragments on an electrophoresis gel.
Lesson Plan
Curated OER

The Clark Family Story: Tracing the Cause of Hemophilia

For Teachers 7th - 12th
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Lesson Plan
Curated OER

Cut-off Genes

For Teachers 9th - 12th
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Lesson Plan
Curated OER

DNA Sequencing Simulation

For Teachers 9th - 12th
High schoolers simulate the Sanger method of DNA sequencing using color pop-beads as a representation of nucleotides and dideoxynucleotides. Students assemble DNA sequences and run their sequences through a "sequencing gel" and sketch...
Lesson Plan
Curated OER

Where's the CAT? a DNA Profiling Simulation.

For Teachers 7th - 12th
Students explore DNA technology. Students participate in a simulation to perform at the basic steps of a DNA profile. They observe copies of DNA sequences, construct DNA probes, and discuss outcomes of their experiment.
Lesson Plan
Curated OER

Simulation of Gene Splicing

For Teachers 10th - 12th
Pupils simulate gene splicing by examining bacteria. They create a bacterial DNA into which they insert the human DNA (gene) that codes for growth hormone. They cut the sites of the enzyme to study how the human DNA can be joined to...
Lesson Plan
Curated OER

DNA Fingerprinting: You Be the Judge!

For Teachers 9th - 12th
Young scholars use their knowledge of DNA fingerprinting to evaluate the use fingerprints in courts, and will address the ethics of establishing a national database of fingerprints.
Lesson Plan
Curated OER

DNA Fingerprinting: You Be the Judge!

For Teachers 9th - 12th
Students explore DNA fingerprinting. Students discover how DNA fingerprinting is done and judge the validity. They evaluate the use of certain prints in courts and address the ethics of establishing a national database of fingerprpints.

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