Curated OER
cDNA Sequencing By Restriction Project
Students try to confirm the sequence of a given cDNA clone using the WWW tools and traditional restriction analysis. They grow the clone, prep the plasmid, cut the plasmid with restriction enzymes and compare their results to what was...
Curated OER
Doggy DNA: The Power of PCR
Students listen as the teacher lectures about Polymerase Chain Reaction, and the technical information about its uses. They collect dog saliva and run/analyze a gel electrophoresis. Students use a computer to integrate information, and...
Curated OER
Genome: The Secret of How Life Works
Students become aware that genetic issues impact many areas of life, such as medicine, food and agriculture, and law. They become aware that there are many ethical issues related to genetics.
Curated OER
Simulated Genetic Counseling Session
Young scholars, in groups, prepare a family history for a family with a genetic condition. They simulate a genetic counseling session and listen to a guest lecture by a genetic counselor.
Curated OER
Gene Regulation Mechanisms
Students explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
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Karyotypes and Inheritance of Chromosomes
Students explore the mode of inheritance of chromosomes. Given a scenario, students use the Human Genome sheet to determine inherited chromosomes. They illustrate the difference between genotype and phenotype. Students develop a model...
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Why do we need Vitamin C in our diet? Or Why do we carry old inactive genes in our genome?
Students explore and explain how mutations in the DNA sequence of a gene may be silent or result in phenotypic change in an organism and in its offspring. They analyze how evolution and biodiversity are the result of genetic changes that...
Curated OER
X or Y- Does it Make a Difference?
Students examine the X and Y chromosomes. In this research instructional activity, students use the 5E instructional activity model as they read articles about human chromosomes then discuss their findings and opinions.
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The Human Geonome Project Structured Controversy
Learners debate government funding of the Human Genome Project. In this ethics lesson, students use the stuctured controversy framework to research the opposing viewpoints regarding project funding.
Curated OER
Cracking the Genetic Code
High schoolers explain what the knowledge of DNA can tell us about ourselves and other organisms and species. They also explore the systematic study of the human genome.
Curated OER
The Human Geonome Project
Students explore the Human Genome Project (HGP). Students research a fact situation, examine genetic data given, and discuss choices available for a solution. Students consider the ethical question and consequences of each choice.
Curated OER
Ethical Applications of Human Genetics
Tenth graders read about, observe case study videos, and participate in live interactive broadcasts, and maintain a log book on all of the activities pertaining to the Human Genome Project.
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Cloning of Plasmid and Spinach DNA
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
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The Cloning of Plasmid and Spinach DNA
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...
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Bioethics and the HGP
Students analyze case studies using the rules and principles of ethics. They comprehend which rules and principles of theics are of great importance to the Human Genome Project. Students participate in mock student hearings.
Curated OER
Find the Index Case
Students investigate the tracking of viral diseases. They view experiments that compare the genome of the virus known to cause the disease from different areas. Students analyze how these scientists try to figure out the relationships...
Curated OER
Who Owns Rights to Pharmacogenetic Information?
Students develop an understanding of the rationale of ownership over scientific information. They research commercial applications of DNA sequences. They analyze how to evaluate medical ethics issues.
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Genetic Research and Liberties
Students examine civil liberties issues in relation to genetic research, and discuss how genetic medical information may be used. They present personal viewpoints about genetic research as it relates to civil liberties
Curated OER
DNA and Individual Differences
Students list differences between DNA-related terms and create a simple DNA circle map. They order terms including human body, organ, tissue, cell, nucleus, etc. from largest to smallest. They discuss differences and similarities among...
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Human Genetics and Heredity
Students choose topics for research based on human genetics and heredity. They conduct research via the Internet and write a brief explanation of the milestone in genetics and heredity and attach it to a class timeline. They share...
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DNA from the Beginning Study Guide
Students complete a study guide using a website which is an animated primer on DNA, genes, and heredity. The Web site is organized around key concepts. The web links and study guide are included.
University of Washington
Pasta Genetics
Four different-shaped and dyed pasta types represent four different alleles. Following a guide sheet, young geneticists practice randomly selecting alleles and discover the traits of the resulting offspring. This is a fun and solid...
Curated OER
The Structure of DNA
Learners describe the structure of the double helix, explain how DNA copies itself, and recognize that the sequence of DNA is what makes each individual unique.
Curated OER
How You Become a Unique Individual
Students investigate how traits are passed from parents to offspring via meiosis and fertilization. They recognize that the combination of alleles forming a gamete is random.