Tri Nucleotide Repeat

Mutations often lead to genetic disorders. The tri-nucleotide repeat leads to an expansion of DNA thanks to errors in the process of DNA replication. Using the informative video, scholars identify genetic disorders related to this error in DNA.

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CCSS: Adaptable
NGSS: Adaptable
Instructional Ideas

  • Provide learners with an example of how mutation expansion occurs in DNA replication
  • Give a visual of the replication of DNA and the roles of helicase and DNA polymerase 
  • Introduce genetic disorders by showing how errors in DNA replication sometimes lead to problems in the DNA
Classroom Considerations

  • Use the description on the webpage to introduce the topic before showing video
  • Refers to the disease but does not introduce it

  • Provides a good visual of how a strand of DNA replicates
  • Identifies one of many ways errors in DNA replication occurs

  • None
Common Core