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LABScI
DNA Structure: Gumdrop Modeling
DNA molecules hold the secrets that make us unique. The fourth of 12 lessons explores the structure of DNA by building candy models. After building the models, young scientists break their models to begin the process of DNA replication....
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...
Cornell University
Extracting DNA
Uncover the basics of DNA structure through exploration activities. Collaborative groups build DNA models and recreate the process of replication. Then, using plant cells such as peas or strawberries, they extract a DNA sample.
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Exploratorium
Breakfast Proteins - Construct a Protein through Cereal Additions
Match my cereal sequence. Pupils view a sequence made by colorful cereal rings and create copies of it. Learners must either remember or write down the sequence to transport the code to another location. Scholars replicate the cereal...
Howard Hughes Medical Institute
Pulse Chase Primer: The Meselson-Stahl Experiment
Experimental design can make or break an experiment. Young scholars analyze the pulse-chase analysis procedure by studying the Meselson-Stahl experiment. Using a video presentation, they discover how the pulse-chase analysis led to the...
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Curated OER
Extracting DNA from Your Cells - Teacher Preparation Notes
Students extract their own DNA from cheek cells. In this biology instructional activity, students explain the replication process. They identify the structure and composition of DNA.
Towson University
Transformation Lab
Transform your class' understanding of genes and antibiotic resistance with the Transformation Lab. Junior geneticists create and observe their own resistant strains of E. coli through research, discussion, and experimentation. The...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
North Carolina State University
Exploring Genetics Across the Middle School Science and Math Curricula
Where is a geneticist's favorite place to swim? A gene pool. Young geneticists complete hands-on activities, experiments, and real-world problem solving throughout the unit. With extra focus on dominant and recessive genes, Punnett...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
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