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US Apple Association
Apples: A Class Act! (Grades 4–6)
Middle schoolers have a bushel of fun as they engage in activities and research core facts about apples. Packed with suggestions for in-class activities and out-of-class research, the colorful 6-page packet is sure to satisfy hungry...
Teach Engineering
Basically Acidic Ink
If you don't want to drink red cabbage juice, here's another use for it—a decoder! Using vinegar and ammonia-based window cleaning liquids as invisible inks, scholars create designs in the second lesson of the series. Red cabbage juice...
Howard Hughes Medical Institute
Biochemistry and Cell Signaling Pathway of the Mc1r Gene
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Exploratorium
Secret Codon - Write a Message in DNA
String up a message. Pupils string together colored beads to code a word or short phrase. Each color represents one of the four DNA bases. Using a combination of three bases, learners create an amino acid that stand for each letter of...
Howard Hughes Medical Institute
Zebrafish and Skin Color
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...
Teach Engineering
Red Cabbage Chemistry
Using the natural pH indicator of red cabbage juice, groups determine the pH of different everyday liquids. As they work, pupils gain an understanding of pH that may help deal with contaminants in the water supply.
Teach Engineering
Pill Dissolving Demo
Plop, plop, fizz, fizz, oh that one is the fastest. The teacher demonstration is the second part of a four-part series. The class observes how different pill types dissolve in simulated stomach acid. They determine which one dissolves...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Serendip
Where Does a Plant's Mass Come From?
Where does the mass for a growing tree come from? Scholars consider a few different hypotheses and guess which is correct. They then analyze data from different experiments to understand which concepts science supports.
Exploratorium
Breakfast Proteins - Construct a Protein through Cereal Additions
Match my cereal sequence. Pupils view a sequence made by colorful cereal rings and create copies of it. Learners must either remember or write down the sequence to transport the code to another location. Scholars replicate the cereal...
Carnegie Mellon University
Ocean Acidification
After brainstorming what they know about ocean acidification, youngsters place eggs in acid to determine the effects on calcium-containing organisms, and add carbon dioxide to solutions with sea shell material to discover the impact on...
Teach Engineering
Inside the DNA
Get your class to take a closer look at DNA. Pupils conduct research to determine the methods used by scientists to analyze the molecular structure of DNA. The class members investigate different types of molecular imaging along with gel...
American Chemical Society
American Chemical Society: Science for Kids: Chemical and Physical Change
Engaging hands-on science lessons for grades 2-6 on chemical and physical changes.
US Environmental Protection Agency
Epa: Determining the P H of Common Substances
In this acid rain experiment the students will be "determining the pH of common substances." This is a great lesson plan for an experiment.