Lesson Plan
Curated OER

COMPARISON OF FOUR-, SIX-, AND EIGHT-bp CUTS IN CALF THYMUS DNA

For Teachers 9th - 12th
Students use this laboratory exercise, restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. Assuming that the four component nucleotides (A, C, T, G) are distributed randomly within a DNA molecule, then any...
Lesson Plan
Curated OER

Biochemistry Detectives

For Teachers 9th - 12th
High schoolers explore the process of chemosynthesis and relate it to the biological communities in cold seeps. In this biochemistry instructional activity students interpret analyses of enzyme activity and draw inferences about...
Lesson Plan
Curated OER

Simulation of Gene Splicing

For Teachers 10th - 12th
Learners simulate gene splicing by examining bacteria. They create a bacterial DNA into which they insert the human DNA (gene) that codes for growth hormone. They cut the sites of the enzyme to study how the human DNA can be joined to...
Lesson Plan
Curated OER

Organic Molecules

For Teachers 9th - Higher Ed
Students explore organic compounds. Using humor, factual and conceptual correctness, students create a skit explaining organic compounds. Students include topics such as sugar, polymerization, unraveling of proteins, and substrates. ...
Lesson Plan
Curated OER

Cell Structure And Function

For Teachers 9th - 10th
In this biology worksheet, students respond to 13 multiple choice questions related to cell structure and function. They identify which are microfilamets and which have a cell wall. Students also describe what chloroplasts are and their...
Lesson Plan
Curated OER

Transcription, Translation, and the Genetics of Microbes

For Teachers 11th - 12th
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
Lesson Plan
Curated OER

DNA Fingerprinting: You Be the Judge!

For Teachers 9th - 12th
Learners use their knowledge of DNA fingerprinting to evaluate the use fingerprints in courts, and will address the ethics of establishing a national database of fingerprints.
Lesson Plan
Curated OER

DNA and RNA Structure and Transcription

For Teachers 9th - 12th
Young scholars compare and contrast the structure of RNA and DNA.They summarize the process of transcription and translation. The lesson uses an inquiry model and the use of codes in DNA.
Lesson Plan
Curated OER

To Smell or Not to Smell, That is the Ester

For Teachers 9th - 12th
Young scholars explain the basic concepts of polymerization. Students participate in a lab to create a crude preparation of carboxyl esterase and test its effectiveness in reducing the residual monomer in an emulsion such as paint.
Lesson Plan
Curated OER

Respiration Challenge

For Teachers 11th - Higher Ed
Students use limited data and their prior knowledge to solve problems focused on various inhibitors of respiration in this lesson plan on cellular respiration in a molecular level. This lesson plan includes a student handout and a...
Lesson Plan
Curated OER

Reaction Rates-Catalysis, Concentration, Surface Area, and Temperature

For Teachers 7th - 11th
Students determine the meanings of concentration, surface area, and catalysis through an experiment. In this lesson about chemical reactions, students participate in an experiment. Students complete three different parts of the...
Lesson Plan
Virginia Department of Education

Physical and Chemical Properties of Water

For Teachers 9th - 12th
How can you effectively provide detailed concepts of water properties to your high school class in a way they find exciting and challenging at the same time? By letting them play, of course! Through a variety of...
Lesson Plan
Curated OER

Molecular Evolution in Plants

For Teachers 9th - 12th
High schoolers are using a paper chromatography study that is suitable for introductory biology. The absorption spectra studies and gel electrophoresis studies are appropriate for students who have complete both introductory biology and...
Lesson Plan
Curated OER

cDNA Sequencing By Restriction Project

For Teachers 9th - 12th
Young scholars try to confirm the sequence of a given cDNA clone using the WWW tools and traditional restriction analysis. They grow the clone, prep the plasmid, cut the plasmid with restriction enzymes and compare their results to what...
Lesson Plan
Curated OER

Selecting Soil Organisms in Compost

For Teachers 12th - Higher Ed
Students conduct an experiment to demonstrate that many of the enzyme systems needed to break down society's wastes exist in nature among the decomposers in a compost pile. They culture compost bacteria on starch agar to examine the...
Lesson Plan
Curated OER

Comparison of Four-, Six-, And Eight-bp Cuts in Calf Thymus Dna

For Teachers 9th - 12th
Students investigate the use of restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. They utilize restrictive endonucleases to cut Thymus DNA and compare results by viewing the DNA fragments on Agarose Gel...
Lesson Plan
Curated OER

Cloning of Plasmid and Spinach DNA

For Teachers 12th - Higher Ed
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
Lesson Plan
Curated OER

The Cloning of Plasmid and Spinach DNA

For Teachers 10th - 12th
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...
Lesson Plan
Virginia Department of Education

Biotechnological Issues and Bioethics

For Teachers 9th - 12th
Culminate a bioethics unit with the implementation of a lesson that incorporates the Socratic method to encourage class feedback and participation. Pupils participate in a discussion on bioethics and morality, complete a...
Lesson Plan
Nuffield Foundation

Investigating the Effect of Temperature on the Activity of Lipase

For Teachers 9th - 12th
How does temperature affect lipase activity? Young scholars conduct an experiment to collect data on the interaction of lipase at different temperatures. They add lipase to a solution of milk, sodium carbonate, and phenolphthalein and...
Lesson Plan
Curated OER

CONSTRUCTION OF A HEMOGLOBIN GENE

For Teachers 9th - 12th
Students use research to see how eight pairs of triplets are equivalent to part of a gene and control a part of heredity. They also understand how red blood corpuscles manufacture normal hemoglobin.
Lesson Plan
Curated OER

Separating a Starch-Glucose Mixture Using Gel Filtration

For Teachers 9th - 12th
Students experiment using the basic principles of gel filtration. They use the gel filtration technique for testing for the presence of specific substances. Students discover that starch is a larger molecule than glucose.
Lesson Plan
Curated OER

Trichinella Forensics

For Teachers 5th - 8th
Students engage in DNA manipulation using forensics techniques. Students investigate topics involved in forensics studies such as cloning, electrophoresis, gene mapping, replication, and transcription.
Lesson Plan
Curated OER

How Is the Genetic Code Ultimately Translated Into a Protein?

For Teachers 9th - 12th
Students examine the functions of mRNA, rRNA and tRNA. They explain the steps in the protein synthesis process. They practice using new vocabulary as well.

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