Curated OER
DNA Sequencing Simulation
Students simulate the Sanger method of DNA sequencing using color pop-beads as a representation of nucleotides and dideoxynucleotides. Students assemble DNA sequences and run their sequences through a "sequencing gel" and sketch what...
Curated OER
Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis
Young scholars create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...
Curated OER
Agarose Gel DNA Quantitation
Students examine agarose gels to compare a known DNA sample to an unknown sample to determine the quantity and size of an unknown DNA sample.
Curated OER
Using Amino Acid Sequences to Show Evolutionary Relationships
Compare protein fragments, count amino acids, and use the information to explore common ancestry. The resource mentions a student worksheet, however, a separate printable worksheet is not provided. The exercises are written into the...
Curated OER
From Restriction Maps to Cladograms
Biology aces analyze restriction maps to determine the relationships among different primate species and then complete a cladogram. Preface this lesson with an explanation of how restriction enzymes are used to create the DNA maps....
Curated OER
DNA Race Track
Twelfth graders simulate a DNA fragment running through a gel electrophoresis in a class activity. Students work in teams as a DNA sample with each person on the team representing a fragment that moves through the gel at a specific speed.
Curated OER
Comparison of Four-, Six-, And Eight-bp Cuts in Calf Thymus Dna
Young scholars investigate the use of restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. They utilize restrictive endonucleases to cut Thymus DNA and compare results by viewing the DNA fragments on Agarose Gel...
Curated OER
Electrophoresis Analogy
Learners participate in a simulation of electrophoresis separation of DNA fragments. They link arms to form DNA fragments with each student representing a nucleotide. As they move through an obstacle course they discover how fragments...
Curated OER
Determination of Phylogenetic Relationships Using Restriction Analysis
Students applied various mathematical analyses to interpret their data. By using the resulting DNA fragment patterns from several enzymes students established a possible evolutionary relationship among the mice.
Curated OER
"Who Done It?" Analysis of Molecular Fingerprints Left At the Scene of the Crime
Learners examine different types of DNA fragments. They record and analyze their results. They determine who is the criminal in the story.
Curated OER
Cutt-Off Genes
Students explore how gene sequence analysis can be used to examine phylogenetic similarities of different organisms. Students work in groups to simulate a gel electrophoresis separation of fragments using poster board to create their gel.
Curated OER
Pharmaceuticals and Treatments
Learners perform an experiment involving reverse transcriptase-polymerized chain reaction HIV replication to better examine the biotechnology used by scientists in pharmaceutical research of infections diseases like HIV. Students examine...
Curated OER
DNA Recombination II
Students model recombination in DNA. They color the DNA sample and cut it out. Students use their "restriction enzymes" to cut the DNA into specific fragments. They separate the fragments using the "gel electrotrophoresis." Students...
Curated OER
Polymerase Chain Reaction (PCR)
Students explore how PCR works through various activities. In this biology lesson, students explain how PCR generate copies of DNA. They simulate the process using an online interactive website.
Curated OER
Genetic Technology
For this genetic worksheet, students will match 6 terms associated with gene engineering to their correct definition. Then students will complete a table indicating if the vector is mechanical or biological. Finally, students will...
Towson University
Chestnut Tree Lab
What will your class learn in a curious tale of a fungus, a virus, and a chestnut tree? Biology scholars discover the world of viral biocontrols through a DNA restriction lab. Groups research the decline of the American chestnut tree at...
Curated OER
DNA
this DNA Powerpoint describes replication, and communicates the concept that viral DNA can program cells.
Curated OER
Fly Forensics
Freddy's Friendly Fruit Market is under attack by fruit flies, and it is up to your aspiring biologists to solve the crime! By reading and analyzing the phenotypes, detectives determine which fly is responsible. This memorable assignment...
Curated OER
A Little More Advanced Biotechnology Tools: Better Plasmids
A nice set of information that will help your students understand the process of using recombinant plasmids. DNA hybridization and blotting mechanisms help illustrate expressed genes and the concepts behind the Human Genome Library....
Curated OER
A Little More Advanced Biotechnology Tools; Better Plasmids
After using this DNA and plasmids slide show, the steps of the delicate procedures of southern blotting and DNA libraries should be more clear to your students. Students will read the guidelines and are also prompted to answer questions...
Curated OER
DNA Fingerprinting through a Chemistry Lens
Students explore DNA and restriction enzymes using fragments of DNA separated by electrophoresis on an agarose gel. They analyze the results to see "whodunit".
Curated OER
Cloning of Plasmid and Spinach DNA
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
Curated OER
DNA Fingerprinting
Ninth graders investigate what restriction enzymes do, and explain how a DNA sample can link a suspect to a crime.
Curated OER
The Cloning of Plasmid and Spinach DNA
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...