Concord Consortium
Mutations
Are some mutations more damaging than others? An engaging simulation encourages scholars to alter DNA through insertion, deletion, and substitution. It then forms resulting amino acids—or not—and the resulting protein—or not—depending on...
CK-12 Foundation
Transcription of DNA to RNA: Making mRNA
Transcription means a written copy but how can DNA write a message? The video explains transcription and translation as they relate to DNA and RNA. Then in the interactive, scholars practice base pairing and answer analysis...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Howard Hughes Medical Institute
Creating Phylogenetic Trees from DNA Sequences
How closely are animals related? Check their phylogenetic trees! The use of DNA sequencing altered our understanding of these relationships. Individuals explore and gain a better understanding of how scientists sort, align, and determine...
Howard Hughes Medical Institute
Virochip DNA Microarray
Virochips detect and identify viruses at a higher rate than other tests. Show young scientists how Virochips work to identify existing viruses. They analyze results demonstrating mutations or the evolution of viruses and view videos...
Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Cold Spring Harbor Laboratory
DNA Is Only the Beginning for Understanding the Human Genome
Mario Capecchi requested funding for a new procedure targeting genes and was rejected. Four years later, after he proved it worked, the NIH apologized and funded his research. Use an online interactive to learn about his research and the...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Cold Spring Harbor Laboratory
One Gene Makes One Protein
Very few universities still offer a master's degree in the ecology of grasses, but that was the degree that led George Wells Beadle to an interest in genetics and later a Nobel Prize. Scholars learn about the discoveries of Dr. Beadle...
Howard Hughes Medical Institute
RNA Diversity
Messenger RNA, transfer RNA, and ribozymes ... the many faces of RNA. The structure of RNA makes it much more versatile than the very similar DNA. Learners view a slideshow presentation to learn all about the different forms and...
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
Development Balances Cell Growth and Death
Cells demonstrate a life cycle like other living things, but what if death was no longer part of the cycle? Learn about the important balance requiring death to continue functioning. An online interactive introduces a group of scientists...
Howard Hughes Medical Institute
Bacterial Quorum Sensing
The marine bacteria vibrio harveyi helps with DNA repair in humans. Understanding how to manipulate and genetically mutate this bacteria fascinates researchers. Young scientists observe two different mutations, predict the resulting...
Cold Spring Harbor Laboratory
Evolution Begins with the Inheritance of Gene Variations
Connect Mendelian genetics with Darwinian theories. An interactive lesson lets pupils explore how George Shull used research from other scientists to explore genetic variation. The resource outlines the statistical analysis of genetic...
University of Utah
University of Utah: Learning Center: Learn Genetics:the Outcome of Mutation
Mutation is a process that changes a DNA sequence. But how does a difference in a gene's DNA sequence (or genotype) lead to a difference in an observable trait (or phenotype)?
Cold Spring Harbor Laboratory
Dna Learning Center: Disease & Mutation: How Gleevec Works
Chronic myeloid leukemia is a disease caused by a genetic mutation that gives rise to this abnormal protein molecule. The abnormal protein triggers the bone marrow to release dangerous numbers" of white blood cells. Gleevec, the thin...
Concord Consortium
The Molecular Logic Database: Mutations: Changing the Genetic Code
Students will learn about the different types of mutations and how they work. They will compare the effect of these different types of mutations in DNA, including nucleotide substitution, nucleotide insertion, and nucleotide deletion....
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Disease & Mutation: Dna Damage
See how mutations in DNA can affect human cells, and how these mutations can even be corrected by biochemical repair work. [1:05]
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Disease & Mutation: Tumor Growth
See how cell division is essential for healthy growth of an organism, and how complex genetic mechanisms have evolved to switch cell division on and off at the proper time for normal development. [0:50]
Cold Spring Harbor Laboratory
Dolan Dna Learning Center: Disease & Mutation: Sickle Cell
A brief overview of Sickle cell anemia, a genetic disease that affects hemoglobin in the blood. [1:30]
University of Utah
University of Utah: Learning Center: learn.genetics: Making Sn Ps Make Sense
Find out how tiny variations in DNA can help scientists predict humans' response to drugs or to disease risk.
University of Colorado
University of Colorado: Ph Et Interactive Simulations: Gene Machine: The Lac Operon
Build a gene network. The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.
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