Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Curated OER
RNA Worksheet
In this RNA learning exercise, learners determine the function of mRNA and tRNA and create an mRNA strand from a given DNA strand. Students describe and compare the 3 types of RNA. This learning exercise has 1 drawing, 2 fill in the...
Curated OER
Enhancing Students' Problem-Solving Abilities
Students analyze the results of a hypothetical cloning experiment using a restriction endonuclease map obtained from an on-line data source. They answer the question, "How can I tell if the DNA I have obtained from this hypothetical...
Curated OER
Polymerase Chain Reaction (PCR)
Students explore how PCR works through various activities. In this biology lesson, students explain how PCR generate copies of DNA. They simulate the process using an online interactive website.
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Curated OER
Fly Forensics
Freddy's Friendly Fruit Market is under attack by fruit flies, and it is up to your aspiring biologists to solve the crime! By reading and analyzing the phenotypes, detectives determine which fly is responsible. This memorable assignment...
Curated OER
From Gene to Protein ~ Transcription and Translation
Translate the process of protein synthesis to your molecular biologists with this instructional activity. It consists of reading, completing a table as a summary, comprehension questions, and a modeling activity for both transcription...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Curated OER
The Cytochrome-C Lab
Students examine a method biologists use to try to determine relationships. They examine how amino acid sequences have been determined for a number of proteins, and how scientists can make inferences about DNA based on the amino acid...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Curated OER
The Six Kingdoms
In this evolution worksheet, students will determine the evolutionary relationships among organisms using cladograms and phylogenetic diagrams. This worksheet has 13 short answer questions and 3 multiple choice questions.
Curated OER
Identifying Disease Genes using BLAST
Students navigate the National Center for Biological Information (NCBI) website and BLAST program to conduct a variety of biological assignments.
Howard Hughes Medical Institute
Hhmi: Bio Interactive: Understanding Sequence Assembly
A series of lecture clips helps explain how DNA sequencing is done by using the analogy of shredding multiple copies of a book and then reassembling the text by finding overlapping fragments. The ultimate goal of DNA sequencing is to...
Khan Academy
Khan Academy: Dna Sequencing
Learn how the sequence of nucleotide bases (As, Ts, Cs, and Gs) in a piece of DNA is determined.
Cold Spring Harbor Laboratory
Dna From the Beginning: A Gene Is a Sequence of Nucleotides
Genes are actually a specific sequence of DNA and they have a clear start and stop. Learn about the discovery and sequencing of genes at this site. This multimedia article includes animations, pictures, video, biographical information,...
Other
Digital World Biology: Blast Tutorial
A series where students see how to submit a nucleotide sequence, compare it to other sequences using blastn, and interpret some of the results.
University of Missouri
University of Missouri: Biotech Adventure: Dna Structure
DNA Helix, DNA structure, DNA bases, Nucleotides, strands of DNA, Bonding in DNA, and bonding between bases are the topics delved into in this thorough site.
Cold Spring Harbor Laboratory
Dna Learning Center: Dna Molecule, Dna Unzip
The DNA double helix contains two sequences of nucleotide code letters than run along the molecule. Untwist the spiral and DNA can be seen as two parallel strands. That's why its sometimes called the double helix. Unzip the strands and...
CK-12 Foundation
Ck 12: Life Science: Transcription of Dna to Rna
[Free Registration/Login may be required to access all resource tools.] DNA is located in the nucleus. Proteins are made on ribosomes in the cytoplasm. Remember that information in a gene is converted into mRNA, which carries the...
National Health Museum
Access Excellence: Dna Dry Lab
This lab illustrates how the order of nucleotides in DNA determines the order of amino acids in proteins. Relates DNA function to that of RNAand provides an exercise to demonstrate how mutations may occur. Includes a lesson plan and...
National Health Museum
Access Excellence: Making a Phylogenetic Tree Lesson Plan
Constructing phylogenetic trees may be a daunting task for students, but this lesson plan is a simulation of what molecular biologists must do to determine relationships. This plan is for students who have a good grasp of DNA structure...