Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Curated OER
Fly Forensics
Freddy's Friendly Fruit Market is under attack by fruit flies, and it is up to your aspiring biologists to solve the crime! By reading and analyzing the phenotypes, detectives determine which fly is responsible. This memorable assignment...
Curated OER
From Gene to Protein ~ Transcription and Translation
Translate the process of protein synthesis to your molecular biologists with this instructional activity. It consists of reading, completing a table as a summary, comprehension questions, and a modeling activity for both transcription...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
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Nucleic Acid
In this chromosome worksheet learners complete a crossword puzzle by answering questions on DNA, nucleic acids, nucleotides and RNA.
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BLAST Algorithm
Students explore a series of activities on using BLAST. In this biology lesson plan, students explain the significance of BLAST in DNA query. They give real world applications of BLAST.
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Electrophoresis Analogy
Students participate in a simulation of electrophoresis separation of DNA fragments. They link arms to form DNA fragments with each student representing a nucleotide. As they move through an obstacle course they discover how fragments...
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More Basic Biotechnology Tools
You can use these slides to explain the many complicated steps of the Polymerase Chain Reaction. The diagnostic and forensic uses of gel electrophoresis are detailed. This PowerPoint could be used to communicate facts, or to prompt...
Curated OER
DNA and Genes
Students analyze the structure of DNA. They describe how the structure of DNA enables it to reproduce itself accurately. Students discuss genes and the sequence of nucleotides occur in DNA.
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Protein Factory
Students examine protein synthesis and how DNA is transcribed. For this investigative lesson students play a role in the messenger RNA when it creates nucleotides.
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The Code of Life
Students study genes, DNA and medical research. They watch "The Code of Life" video and answer discussion questions regarding the transcription and translation of DNA and how errors in these processes and mutations in DNA can produce...
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Protein Factory
Pupils discuss the steps of protein synthesis before acting out the process as a class. They are assigned specific roles and receive an instruction card and get materials listed in order to perform their role. Students switch roles and...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Curated OER
The Cytochrome-C Lab
Students examine a method biologists use to try to determine relationships. They examine how amino acid sequences have been determined for a number of proteins, and how scientists can make inferences about DNA based on the amino acid...
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Nutrient Biochemistry
In this nutrient biochemistry worksheet, students complete the blanks with information about nucleic acids and the process. Students also draw a figure referenced in the text given.
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Protein Synthesis
In this biology worksheet, students complete a crossword puzzle with 35 questions on protein synthesis. They identify the different parts of the cell involved in the process.
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Who Owns Rights to Pharmacogenetic Information?
Students develop an understanding of the rationale of ownership over scientific information. They research commercial applications of DNA sequences. They analyze how to evaluate medical ethics issues.
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Scientist Simulation
Students imagine themselves working as research scientists completing the end-steps of a molecular research project and interpreting the data. They compare the gene sequences of normal and abnormal mice and evaluate the protein product...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Curated OER
The Six Kingdoms
In this evolution activity, learners will determine the evolutionary relationships among organisms using cladograms and phylogenetic diagrams. This activity has 13 short answer questions and 3 multiple choice questions.
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Identifying Disease Genes using BLAST
Students navigate the National Center for Biological Information (NCBI) website and BLAST program to conduct a variety of biological assignments.
Curated OER
Construction of a Hemoglobin Gene
Pupils see how eight pairs of triplets are equivalent to part of a gene and control a part of heredity. They comprehend how blood corpuscles manufacture normal hemoglobin. Students already comprehend that genes control the synthesis of...