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Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book,...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Curated OER
Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Curated OER
Monstrous Mutations
Students investigate mutations and simulate their mutation while trying to collect food. In this mutations lesson plan, students pick an identified mutation out of a paper bag. They simulate their mutation while trying to collect food...
Curated OER
Selection and Variation in the Egyptian Origami Bird
Using origami paper birds, your biology class will experiment with mutations and natural selection to determine wing position, length, and width. It would be helpful to provide a worksheet to go with the activity that includes a...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Science 4 Inquiry
"Something Old, Something New..."
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Curated OER
Mutations and Cancer
High schoolers study how cancer cells mutate and affect cell division. In this investigative lesson students view a PowerPoint presentation learn the seven warning signs of cancer.
Curated OER
Mutations--Preexisting or Acquired?
Students explore the reasoning and experimental approaches to mutations. They expose a culture of E. coli to virulent bacteriophage and observe whether mutations of the cells existed previously or if the bacteria mutated as a response...
Curated OER
Mutations--Preexisting or Acquired?
Young scholars state the controls and variables of the Newcombe spread experiment. They state a hypothesis for the Newcombe spread experiment. Students distinguish between the characteristics of a preexisting mutations and those of an...
Curated OER
Building a DNA Molecule, Mitosis in Motion and Mutation Gossip
Students explore three lab experiments involving DNA, mitosis, and mutation. They complete activities and play games to review DNA, mitosis and mutation concepts. They build a DNA molecule and create flip cards representing mitosis in...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Agriculture in the Classroom
Design 'Y'er Genes
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Curated OER
Tracing Genetic Ancestry Using DNA Microarrays
High school learners read and discuss an article about genetic ancestry and genetic ancestry testing. They complete a paper and pencil activity that mimics the function of a DNA microarray and consider the ethics of genetic testing in...
Curated OER
Gene Action/Mutation Worksheet
Students define the following terms: mutation, mutagen and give examples of how they work. They also define and illustrate a point mutation. Students define and illustrate a frame shift mutation and name two types of frame shift...
New York State Education Department
Regents High School Examination: Living Environment 2010
This exam covers every topic in a typical first-year biology course. A wide variety of question styles gives high schoolers every opportunity to show what they know. Why start from scratch when a comprehensive final exam is easily...
Curated OER
Gene Action and Mutation
Students review terms related to DNA structure and function. They complete a variety of worksheets in small groups or in pairs reflecting the unit's concepts regarding DNA. They submit their worksheets for grading.
Beyond Benign
Lucky Brand Genes: Chromosome Cookies
Mutations are not just deformed creatures we see in movies—they happen every day! Scholars study the different types of genetic mutations in the 12th installment of a series of 18 lessons. A creative activity uses candy and other food...
Curated OER
Evolution
Explore the concept of evolution and cell biology; your class can work in groups to use the internet to view websites on evolution, take a quiz, and complete a lab activity.
Serendip
Understanding the Biology of Cancer
After initial exposure to a carcinogen, a cancer diagnosis often takes more than a decade due to the slow buildup of mutated cells in the body. Scholars learn about the biology of cancer with a worksheet and discussion questions. They...
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