Lesson Plan
Serendip

The Molecular Biology of Mutations and Muscular Dystrophy

For Teachers 9th - 12th
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Lesson Plan
Curated OER

Selection and Variation in the Egyptian Origami Bird

For Teachers 9th - 12th
Using origami paper birds, your biology class will experiment with mutations and natural selection to determine wing position, length, and width. It would be helpful to provide a worksheet to go with the activity that includes a...
Lesson Plan
Serendip

Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection

For Teachers 6th - 12th Standards
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Lesson Plan
Serendip

UV, Mutations, and DNA Repair

For Teachers 9th - 12th
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Lesson Plan
Howard Hughes Medical Institute

The Making of the Fittest: The Birth and Death of Genes

For Teachers 9th - Higher Ed
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Lesson Plan
Curated OER

Mutations and Cancer

For Teachers 9th - 12th
Students study how cancer cells mutate and affect cell division.  In this investigative instructional activity students view a PowerPoint presentation learn the seven warning signs of cancer. 
Lesson Plan
Curated OER

Allele and Phenotype Frequencies in Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Lesson Plan
Virginia Department of Education

Genetic Variation and Mutations

For Teachers 9th - 12th
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book,...
Lesson Plan
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Curated OER

Genes, DNA, and Mutations

For Teachers 9th - 12th
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Lesson Plan
Science 4 Inquiry

"Something Old, Something New..."

For Teachers 9th - 12th Standards
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Lesson Plan10:25
Howard Hughes Medical Institute

The Making of the Fittest: Natural Selection and Adaptation

For Students 8th - Higher Ed Standards
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Lesson Plan
Curated OER

The Clark Family Story: Tracing the Cause of Hemophilia

For Teachers 7th - 12th
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Lesson Plan
Curated OER

Monstrous Mutations

For Teachers 7th - 10th
Learners investigate mutations and simulate their mutation while trying to collect food. For this mutations lesson plan, students pick an identified mutation out of a paper bag. They simulate their mutation while trying to collect food...
Lesson Plan
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Howard Hughes Medical Institute

Got Lactase? The Co-Evolution of Genes and Culture

For Teachers 8th - 12th Standards
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Lesson Plan
Curated OER

Tracing Genetic Ancestry Using DNA Microarrays

For Teachers 9th - 12th
High school learners read and discuss an article about genetic ancestry and genetic ancestry testing. They complete a paper and pencil activity that mimics the function of a DNA microarray and consider the ethics of genetic testing in...
Lesson Plan
Curated OER

Mutations--Preexisting or Acquired?

For Teachers 9th - 12th
Students state the controls and variables of the Newcombe spread experiment. They state a hypothesis for the Newcombe spread experiment. Students distinguish between the characteristics of a preexisting mutations and those of an...
Lesson Plan
Curated OER

Gene Action/Mutation Worksheet

For Teachers 9th - 12th
Learners define the following terms: mutation, mutagen and give examples of how they work. They also define and illustrate a point mutation. Students define and illustrate a frame shift mutation and name two types of frame shift...
Lesson Plan
Howard Hughes Medical Institute

Icefish Adaptations

For Teachers 7th - 12th Standards
What adaptations exist in order for icefish to survive the subfreezing temperatures of the Antarctic Ocean? Middle and high schoolers can find out through watching a related 13-minute video and performing a simple investigation to...
Lesson Plan
Serendip

Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment

For Teachers 9th - 12th Standards
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Lesson Plan
Agriculture in the Classroom

Design 'Y'er Genes

For Teachers 9th - 12th Standards
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Lesson Plan
Curated OER

The Selection and Variation in the Egyptian Origami Bird

For Teachers 9th - 10th
Learners participate in a contrived natural selection simulation in which they build and modify simple paper airplanes. They study divergent and convergent evolution and how it is isolated in sub-populations.
Lesson Plan
Curated OER

Pharmaceuticals and Treatments

For Teachers 12th - Higher Ed
Students perform an experiment involving reverse transcriptase-polymerized chain reaction HIV replication to better examine the biotechnology used by scientists in pharmaceutical research of infections diseases like HIV. Students examine...
Lesson Plan
Curated OER

How Mutations Lead to Changes in Cell Structure and Function

For Teachers 9th - 12th
Students investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare...
Lesson Plan
Curated OER

Evolution

For Teachers 6th - 11th
Explore the concept of evolution and cell biology; your class can work in groups to use the internet to view websites on evolution, take a quiz, and complete a lab activity.

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