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Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Curated OER
Selection and Variation in the Egyptian Origami Bird
Using origami paper birds, your biology class will experiment with mutations and natural selection to determine wing position, length, and width. It would be helpful to provide a worksheet to go with the activity that includes a...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Curated OER
Mutations and Cancer
Students study how cancer cells mutate and affect cell division. In this investigative instructional activity students view a PowerPoint presentation learn the seven warning signs of cancer.
Curated OER
Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book,...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Science 4 Inquiry
"Something Old, Something New..."
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Curated OER
Monstrous Mutations
Learners investigate mutations and simulate their mutation while trying to collect food. For this mutations lesson plan, students pick an identified mutation out of a paper bag. They simulate their mutation while trying to collect food...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Tracing Genetic Ancestry Using DNA Microarrays
High school learners read and discuss an article about genetic ancestry and genetic ancestry testing. They complete a paper and pencil activity that mimics the function of a DNA microarray and consider the ethics of genetic testing in...
Curated OER
Mutations--Preexisting or Acquired?
Students state the controls and variables of the Newcombe spread experiment. They state a hypothesis for the Newcombe spread experiment. Students distinguish between the characteristics of a preexisting mutations and those of an...
Curated OER
Gene Action/Mutation Worksheet
Learners define the following terms: mutation, mutagen and give examples of how they work. They also define and illustrate a point mutation. Students define and illustrate a frame shift mutation and name two types of frame shift...
Howard Hughes Medical Institute
Icefish Adaptations
What adaptations exist in order for icefish to survive the subfreezing temperatures of the Antarctic Ocean? Middle and high schoolers can find out through watching a related 13-minute video and performing a simple investigation to...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Agriculture in the Classroom
Design 'Y'er Genes
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Curated OER
The Selection and Variation in the Egyptian Origami Bird
Learners participate in a contrived natural selection simulation in which they build and modify simple paper airplanes. They study divergent and convergent evolution and how it is isolated in sub-populations.
Curated OER
Pharmaceuticals and Treatments
Students perform an experiment involving reverse transcriptase-polymerized chain reaction HIV replication to better examine the biotechnology used by scientists in pharmaceutical research of infections diseases like HIV. Students examine...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
Students investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare...
Curated OER
Evolution
Explore the concept of evolution and cell biology; your class can work in groups to use the internet to view websites on evolution, take a quiz, and complete a lab activity.
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