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BC Open Textbooks
Concepts of Biology – 1st Canadian Edition
How diverse are living things? Individuals explore topics such as cells as the foundation for life, cell division and genetics, molecular biology, and animal reproduction using an open resource Biology textbook. They learn key terms...
Agriculture in the Classroom
Design 'Y'er Genes
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Pace University
Grades 9-10 Energy Sources
Alternative energy sources are becoming increasingly important. Learners have the opportunity to explore alternative energy sources using a differentiated instruction unit. They group together based on ability levels, assign roles to...
Pace University
Grades 9-12 Earth Science
How has Earth changed over time? Pupils explore the topic in a differentiated instruction unit on the geological time scale. After a pre-assessment to gauge knowledge, class members divide into groups based on their ability levels and...
Howard Hughes Medical Institute
Pulse Chase Primer: The Meselson-Stahl Experiment
Experimental design can make or break an experiment. Young scholars analyze the pulse-chase analysis procedure by studying the Meselson-Stahl experiment. Using a video presentation, they discover how the pulse-chase analysis led to the...
Howard Hughes Medical Institute
Fact Patterns: A Film Guide
What does it take to create a scientific theory? Learners attempt to answer the question by studying the work of Charles Darwin and Alfred Russel Wallace. While watching a video, they track observations from each scientist and then look...
Howard Hughes Medical Institute
Following the Trail of Evidence
One important skill in analyzing scientific evidence is identifying facts versus opinions. Scholars identify pieces of evidence from the film The Day the Mesozoic Died and then discuss this evidence in small groups at the end of each act...
Howard Hughes Medical Institute
Pedigrees and the Inheritance of Lactose Intolerance
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
Howard Hughes Medical Institute
Milk—How Sweet Is It?
Have you ever wondered why some people are lactose intolerant? Participants test simulated patients in a hands-on lab activity to find out! They learn about lactose intolerance by performing an experiment, analyzing data, and drawing...
Cold Spring Harbor Laboratory
Genes Can Be Moved Between Species
Biotechnology changes lives every day, but how did it all start? Learn about Cohen and Boyer's technique for recombinant DNA and the founding of this new scientific study. Then, scholars use the online interactive to discover how Hanahan...
Howard Hughes Medical Institute
Color Variation Over Time in Rock Pocket Mouse Populations
While many mutations are neutral, those that appear advantageous increase in frequency in a population. Scholars use illustrations to make predictions about populations of mice. They follow it up with a video to confirm or refute their...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Howard Hughes Medical Institute
Biochemistry and Cell Signaling Pathway of the Mc1r Gene
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Howard Hughes Medical Institute
Population Genetics, Selection, and Evolution
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
Cold Spring Harbor Laboratory
Living Things Share Common Genes
Everything evolved from a common ancestor, but how did modern plants and animals develop so many more genes? Scholars use an online interactive to learn about the process. They begin to understand common genes with an animation, multiple...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
Development Balances Cell Growth and Death
Cells demonstrate a life cycle like other living things, but what if death was no longer part of the cycle? Learn about the important balance requiring death to continue functioning. An online interactive introduces a group of scientists...
Cold Spring Harbor Laboratory
Different Genes Are Active in Different Kinds of Cells
Personalized medicine prevents many trial-and-error scenarios when time counts the most. Learn how gene expression and screening genomes improves health outcomes in cancer patients, those with auto-immune disorders, and more. An online...
Cold Spring Harbor Laboratory
Genes Can Be Turned On and Off
Regulations exist in many places from business to schools, but what about in our genes? Learn about gene regulation with an online interactive. It uses an animation to introduce the topic, many photographs of the scientists best known...
Cold Spring Harbor Laboratory
Some DNA Can Jump
Some people have a natural ability to jump, but did you know DNA also naturally jumps? Learn about the fun habit by looking at the research of a pioneering female scientist. Barbara McClintock fought prejudice and surpassed her mentors...
Cold Spring Harbor Laboratory
Some DNA Does Not Encode Protein
Roy John Britten easily earned a PhD in nuclear physics—but he found painting with water colors too difficult. Young scientists learn about Britten's life, career, and research with an online interactive. They read a biography, view...
Cold Spring Harbor Laboratory
DNA Is Packaged in a Chromosome
Roger Kornberg, the oldest son of two biochemists, won the 2006 Nobel Prize in Chemistry. Learn about Kornberg and his scientific research with an animation, videos, biography, and an applied problem-solving activity. A summary and...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...