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Howard Hughes Medical Institute
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
Gene switches work similarly to light switches in controlling one feature of their environments. Scholars study the Pitx1 gene in a specific type of fish. They learn the different ways this switch controls various body parts and...
Cold Spring Harbor Laboratory
A Gene Is a Discrete Sequence of DNA Nucleotides
Frederick Sanger won two Nobel prizes for protein sequencing and DNA sequencing. Young scientists learn about Dr. Sanger's research and amazing discoveries. They read an article and a biography, view videos and animations, and apply...
Cold Spring Harbor Laboratory
A Half DNA Ladder Is a Template for Copying the Whole
The experiment known as one of the most beautiful experiments in biology changed the way we think about DNA. Learn about the experiment and the scientists who designed it—as well as the scientists who built on the results—with an online...
Cold Spring Harbor Laboratory
A Gene Is Made of DNA
Does a protein or DNA store genetic instructions for life? Follow the research from the 1920's experiments on mice through the 1940's experiments on bacteria to learn the answer to the difficult question. Scholars use an online...
Cold Spring Harbor Laboratory
Mendelian Genetics Cannot Fully Explain Human Health and Behavior
The breakthrough of Mendelian genetics solved many puzzles for biologists. Then, scientists decided to apply the theory to human behavior. Learn the story and struggle of finding a genetic explanation for hobbies, interests, and mental...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Cold Spring Harbor Laboratory
Higher Cells Incorporate an Ancient Chromosome
Chromosomes contain keys to history including links from royalty to Neanderthals. Young scientists learn about Ivan Wallin's research into chromosomes with an animation and videos. Then, the concept connects to mysteries related to...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Cold Spring Harbor Laboratory
DNA Is Packaged in a Chromosome
Roger Kornberg, the oldest son of two biochemists, won the 2006 Nobel Prize in Chemistry. Learn about Kornberg and his scientific research with an animation, videos, biography, and an applied problem-solving activity. A summary and...
Las Cumbres Observatory
Craters in the Classroom
Laws of motion apply both in space and on Earth. Young experimenters model object impact on the Earth and moon. They use data to determine the effect mass and velocity have on the resulting craters and how that relates to the energy of...
NASA
The Heat is On: Urban Heat Islands, Detection Strategies, and Mitigation Solutions
It's sure getting hot out there! Scholars analyze satellite data on land use and surface temperatures, and then learn how to ground truth satellite data through an activity. They apply technology to identify urban heat islands and...
Curated OER
Natural Selection
Kids act as scientists and preditors in this short natural selection activity; they collect and analyze data, then apply their new knowledge to real-world examples of natural selection. The layout of the worksheet is easy enough to use...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Curated OER
Math in Science-Using Temperature Scales
In this temperature scales activity, students are given the equations to convert from Fahrenheit to Celsius and from Celsius to Fahrenheit. They apply to equations and convert given temperatures.
Curated OER
Blast Off
In this physical science exploration, small groups place a piece of antacid tablet into a film canister and step back to time how long it takes for the top to pop. They repeat the activity, altering either the amount or temperature of...
Curated OER
Who Wants to be a Millionaire? Solar System
Fifteen questions about our solar system make up this interactive review game. It was written by a teacher in the UK, and therefore the monetary winnings for answering correctly are in pounds. The content applies, however, to any...
Curated OER
Magnetism
For this science worksheet, students apply themselves to the acquisition of new vocabulary while solving the crossword puzzle.
Curated OER
Motion
For this science worksheet, students apply themselves to the acquisition of new vocabulary while solving the crossword puzzle.
Curated OER
The Nervous System: Basic Organization and Function
A vintage worksheet on the basic structure and function of the nervous system awaits your beginning biologists. Although it pertains to a textbook chapter reading, the content is relevant to any introductory unit on the nervous system....
Discovery Education
Sonar & Echolocation
A well-designed, comprehensive, and attractive slide show supports direct instruction on how sonar and echolocation work. Contained within the slides are links to interactive websites and instructions for using apps on a mobile device to...
Institute of Electrical and Electronics Engineers
Toxic Popcorn Design Challenge
Engineering enthusiasts are sure to explode in understanding as they practice the engineering design process (EDP). A container of "toxic popcorn" is placed in the classroom. Teams must work together to devise a method for removing it...
Captain Planet Foundation
Solar Cooking Race
Study heat transfer with activities that focus on how heat energy works. Using a solar cooker, ice cubes, and heat transfer bracelets, kids experiment and record what they find by keeping ice cubes cold and vegetables hot.
NASA
Rain Gauge Activity
Complete teacher narrative and presentation slides for teaching about Earth's water make up the bulk of this lesson. Embedded within the slide show, you will find videos about the water cycle, keeping track of the limited supply of fresh...
National Library of Medicine
Your Environment, Your Health: Air Quality
Some scientists argue that air pollution now causes more deaths than smoking. The second unit in a six-part series focuses on air quality. Scholars learn what's in the air, how clean the air around their school is, and what they can do...
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